Special Issue "Hybrid Catalysts for Asymmetric Catalysis"
Deadline for manuscript submissions: closed (15 June 2020).
Interests: organometallic chemistry; asymmetric catalysis; hybrid catalysts; transition metal-based anticancer drugs
Biological macromolecules, in general, possess the ability to selectively discriminate substrates and represent a target for specific active molecules. Otherwise, there are many chemical transformations catalyzed by transition metals, which have not been observed to occur enzymatically. Starting from these premises, a hybrid catalyst may combine some of the most attractive features of homogeneous and enzymatic catalysts. The development of a hybrid catalyst results, in fact, from the combination of a biomolecular scaffold (e.g., proteins, DNA, or peptides) with an active catalytic moiety. The three key parameters in the design of an artificial metalloenzyme can be summarized by the choice of transition metal catalyst, principally guided by the desired catalytic activity; by the choice of biomolecular scaffold, through two different strategies, de novo design or the modification of an existing natural enzyme or protein; and, finally, by the attachment mode between the transition metal catalyst and the scaffold.
This Special Issue covers all the indicated aspects of the design of a hybrid catalyst and its applications in asymmetric catalytic reactions, both as original research articles and as reviews.
Dr. Isabella Rimoldi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Asymmetric catalysis
- Hybrid catalysts
- Artificial metallo-enzymes
- Transition metal complexes
- Biological scaffold interactions