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Special Issue "Current Trends in Ginseng Research"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 March 2020.

Special Issue Editor

Prof. Dr. Deok-Chun Yang
E-Mail Website
Guest Editor
Graduate School of Biotechnology and Department of Oriental Medicinal Materials and Processing, College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do 17104, Republic of Korea
Interests: new ginseng resource development; ginseng-based nanoparticles; in vitro screening of ginseng materials; cultured roots of mountain ginseng (crmg); novel ginseng compound synthesis and bioconversion; hybrid and cultivar development; ginseng abiotic and biotic stress resistance

Special Issue Information

Dear Colleagues,

Ginseng is the common name for plants in the genus Panax, and the most beneficial phytochemical in the Panax species—ginsenoside—has numerous theraputic benefits. Other pseudo-ginsengs include Dendropanax morbifera, Gynostemma plantphylum, Withania sominifera, Codonopsis lanceolata, Eleutherococcus senticosus, and Panax vietnamensis. These plants are well-known for their adaptogen activities, which have been used to enhance human health since ancient times. While various functional studies have been conducted to prove the traditional beliefs about these plants using evidence-based science, more effort is needed to enhance the therapeutic values with empirical datasets. In addition, various technologies, such as bioconversion and nano-biotechnology, have been applied to address the limitations that exist in the molecular size of ginsenoides and are implicated in various products. For this Special Issue, we welcome studies that present research outcomes on therapeutic applications, ginseng-based nanoparticles, cosmetic applications, novel ginseng resources, ginseng saponins and their bioconversion, and secondary metabolites.

Prof. Dr. Deok Chun Yang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Ginseng-based nanoparticles
  • Metal nanoparticles
  • Novel ginseng resources
  • Drug formulations
  • Saponins and their conversion
  • Mass production

Published Papers (1 paper)

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Research

Open AccessArticle
Improved Antioxidant, Anti-inflammatory, and Anti-adipogenic Properties of Hydroponic Ginseng Fermented by Leuconostoc mesenteroides KCCM 12010P
Molecules 2019, 24(18), 3359; https://doi.org/10.3390/molecules24183359 - 16 Sep 2019
Abstract
Hydroponic ginseng (HPG) has been known to have various bio-functionalities, including an antioxidant effect. Recently, fermentation by lactic acid bacteria has been studied to enhance bio-functional activities in plants by biologically converting their chemical compounds. HPG roots and shoots were fermented with Leuconostoc [...] Read more.
Hydroponic ginseng (HPG) has been known to have various bio-functionalities, including an antioxidant effect. Recently, fermentation by lactic acid bacteria has been studied to enhance bio-functional activities in plants by biologically converting their chemical compounds. HPG roots and shoots were fermented with Leuconostoc mesenteroides KCCM 12010P isolated from kimchi. The total phenolic compounds, antioxidant, anti-inflammatory, and anti-adipogenic effects of these fermented samples were evaluated in comparison with non-fermented samples (control). During 24 h fermentation of HPG roots and shoots, the viable number of cells increased to 7.50 Log colony forming unit (CFU)/mL. Total phenolic and flavonoid contents of the fermented HPG roots increased by 107.19% and 645.59%, respectively, compared to non-fermented HPG roots. The antioxidant activity of fermented HPG, as assessed by 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), β-carotene-linoleic, and ferric reducing antioxidant power (FRAP) assay, was also significantly enhanced. In an anti-inflammatory effect of lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, the nitric oxide content and the expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) decreased when treated with fermented samples. Simultaneously, lipid accumulation in 3T3-L1 adipocyte was reduced when treated with fermented HPG. Fermentation by L. mesenteroides showed improved antioxidant, anti-inflammatory and anti-adipogenic HPG effects. These results show that fermented HPG has potential for applications in the functional food industry. Full article
(This article belongs to the Special Issue Current Trends in Ginseng Research)
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