Fragrant Molecules with Pharmacological Activities
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (15 March 2021) | Viewed by 89609
Special Issue Editor
Special Issue Information
Dear Colleagues,
People and animals recognize fragrances (compounds drifting in the air) using their nose. Actually, fragrance is one word among many used to describe this quality; others include words like smell (the most common expression), odor, scent, aroma, fragrance, stench, or stink. In order for a scent to be recognized, it is necessary for gaseous molecules to be in the air so they can be taken into the body via the nasal mucosa and lung. These smell molecules may have chances to act as pharmaceutics, although there are only a few types of molecules that are capable of existing intravenously.
In the past (and through today), aromatherapy has been a trend in complementary and alternative medicine, and it often features botanical essential oils. Natural botanical scented oils are still very popular as ingredients for perfumes, balms, cosmetics, and toiletries; however, a significant number of scientists have pointed out that aromatherapy cannot be supported by scientific evidence derived from experiments using humans as subjects because the sense of smell in humans is inevitably connected to their personal memories, so the data cannot be objectively described. Recently, a variety of new designs and experimental schemes using animals made it possible to perform smell experiments using mice and rats. Thanks to those experiments, researchers have been able to discover sedative, antianxiety, antidepressant, sleep-promoting, and appetite-enhancing capacities as a result of fragrant molecules administered via inhalation.
This Special Issue is designed to gather scientific papers on fragrant molecules derived from natural products that have pharmacological activities. Phytochemistry of active natural products, pharmacological studies on fragrant natural products administered via inhalation administration, studies on possible mechanisms of action of botanical fragrances, or any other relevant issues can be discussed. Studies on fragrant molecules that have pharmacological activities when administered via inhalation will be given preference over studies on other routes of administration such as intravenous or intraperitoneal administration.
Prof. Dr. Michiho Ito
Guest Editor
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Keywords
- Fragrant molecules
- Aromatic compounds
- Pharmacology of fragrance
- Pharmacology of volatile compounds
- Inhalation administration
- Vapor administration
- Essential oils
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