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Special Issue "Fluorescence Spectroscopy of Biomolecules"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 31 October 2019

Special Issue Editor

Guest Editor
Dr. Thomas Gustavsson

LIDYL, Laboratoire Interactions, Dynamiques et Lasers
CEA, CNRS, Université Paris-Saclay
CEA Saclay, 91191 Gif-sur-Yvette France

Website | E-Mail
Interests: fluorescence spectroscopy, femtochemistry and femtobiology; electronic and structural dynamics; photovoltaics

Special Issue Information

Dear Colleagues,

It is my great pleasure to invite you to submit an article for a high-profile Special Issue on the “Fluorescence Spectroscopy of Biomolecules” to be published in Molecules.

This Special Issue aims to highlight research on biomolecules using fluorescence spectroscopy in a very broad sense.

It concerns steady-state as well as time-resolved fluorescence studies, addressing the structural and dynamic properties of the excited biomolecules. Experimental and theoretical studies in solution and in the gas phase aiming at the characterization of the emitting excited state are welcome.

More specifically, it concerns the fluorescence of natural biomolecules, such as nucleic acids, enzymes and proteins, as well as flavins and haemoglobin, in a non-exhaustive list. It also deals with modified fluorescent nucleobases and amino acid analogues, aimed for use as biomarkers. In addition, it also treats studies of fluorescent ligands and drugs interacting with natural biomolecules. In this sense, it addresses fundamental processes such as energy and charge transfer phenomena.

Review articles and perspectives from experts in the field are also welcome.

Dr. Thomas Gustavsson
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • steady-state fluorescence
  • time-resolved fluorescence
  • excited states
  • femtochemistry and femtobiology
  • electronic and structural dynamics
  • relaxation and reaction mechanisms
  • energy transfer
  • electron and charge transfer
  • proton and hydrogen transfer
  • potential energy surfaces
  • conical intersections

Published Papers (1 paper)

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Research

Open AccessArticle
A Green-emitting Fluorescent Probe Based on a Benzothiazole Derivative for Imaging Biothiols in Living Cells
Molecules 2019, 24(3), 411; https://doi.org/10.3390/molecules24030411
Received: 18 December 2018 / Revised: 9 January 2019 / Accepted: 18 January 2019 / Published: 23 January 2019
PDF Full-text (2338 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A new green-emitting fluorescent probe 1 was developed for biothiol detection. The sensing mechanism was considered to be biothiol-induced cleavage of the 2,4-dinitrobenzene- sulfonate group in probe 1 and resulting inhibition of the probe’s photoinduced electron transfer (PET) process. Probe 1 exhibited favorable [...] Read more.
A new green-emitting fluorescent probe 1 was developed for biothiol detection. The sensing mechanism was considered to be biothiol-induced cleavage of the 2,4-dinitrobenzene- sulfonate group in probe 1 and resulting inhibition of the probe’s photoinduced electron transfer (PET) process. Probe 1 exhibited favorable properties such as excellent selectivity, highly sensitive (0.12 µM), large Stokes shift (117 nm) and a remarkable turn-on fluorescence signal (148-fold). Furthermore, confocal fluorescence imaging indicated that probe 1 was membrane-permeable and suitable for visualization of biothiols in living A549 cells. Full article
(This article belongs to the Special Issue Fluorescence Spectroscopy of Biomolecules)
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