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Natural Products as Plant Protection Agents

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 May 2026

Special Issue Editors


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Guest Editor
Department of Microbiology and Biomonitoring, University of Agriculture, al. A. Mickiewicza 21, 31-120 Krakow, Poland
Interests: entomology; biological plant protection; legumes; soil contamination; bioremediation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Organic pesticides, derived from plant extracts, essential oils, and other natural substances, represent a promising alternative to their synthetic counterparts in controlling pests, diseases, and weeds. The growing interest in these solutions stems from their numerous advantages over synthetic pesticides. They are biodegradable, breaking down quickly in the environment and minimizing soil and water contamination. Their complex and often multiple modes of action can make it more difficult for weeds or pests to evolve resistance, offering a long-term strategy for protection management and making them a perfect fit for integrated plant protection and organic farming systems, where the focus is on ecological balance rather than total eradication.

Despite their potential, organic pesticides face several limitations that hinder their widespread adoption. A major challenge is the variable bioactive content in extracts, which can fluctuate based on the plant's growth conditions and harvest time. This leads to an inconsistent efficacy in the field. They also often have a narrow control spectrum, meaning that they may only be effective against a few species, and their activity can be inconsistent due to their low persistence in the environment. Furthermore, formulation and delivery hurdles—such as their volatility and insolubility in water—make it difficult to achieve consistent and selective weed or pest control without harming the crop.

The study of advanced delivery systems, such as emulsions, nanoemulsions, microencapsulation, or mixtures with organic carriers, is welcomed so as to bridge the gap between promising laboratory results and reliable field performance and to make organic pesticides a more viable tool for sustainable agriculture. Studies on the use of natural products in plant protection under field conditions are also appreciated.

Prof. Dr. Janina Gospodarek
Dr. Agnieszka Synowiec
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • advanced delivery systems
  • formulation
  • efficacy
  • control spectrum
  • persistence in the environment
  • field performance
  • sustainable agriculture
  • integrated pest management

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Published Papers

This special issue is now open for submission.
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