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Special Issue "Biopolymers in Drug Delivery and Regenerative Medicine"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 30 April 2020.

Special Issue Editors

Prof. Dr. Carlos A. García-González
E-Mail Website
Guest Editor
Pharmacology, Pharmacy and Pharmaceutical Technology Dept. Faculty of Pharmacy Universidade de Santiago de Compostela 15782 - Santiago de Compostela, Spain
Interests: aerogels; supercritical fluids; regenerative medicine; pharmaceutical technology; 3D-bioprinting; porous materials; scaffolds; biomedical applications
Special Issues and Collections in MDPI journals
Prof. Pasquale Del Gaudio
E-Mail Website
Guest Editor
Department of Pharmacy, University of Salerno, Fisciano, Italy
Interests: polysaccharides; controlled drug delivery; wound healing; aerogels; personalized therapies; pulmonary delivery; micro-nanoencapsulation
Dr. Ricardo Starbird
Guest Editor
Escuela de Química, Instituto Tecnológico de Costa Rica, 30102 Cartago, Costa Rica PO Box 159-7050
Interests: polymer science; structuration of biomass and conductive polymers; composites and electrochemical sensors

Special Issue Information

Dear Colleagues,

Biopolymers including natural (e.g., polysaccharides, proteins, gums, natural rubbers, bacterial polymers), synthetic (e.g., aliphatic polyesters and polyphosphoester), and biocomposites are of paramount interest in regenerative medicine, due to their availability, processability, and low toxicity. Moreover, the structuration of biopolymer-based materials at the nano- and microscale along with their chemical properties are crucial in the engineering of advanced carriers for drug products. Finally, combination products including or based on biopolymers for controlled drug release offer a powerful solution to improve the tissue integration and biological response of these materials. Understanding the drug delivery mechanisms, efficiency, and toxicity of such systems may be useful for regenerative medicine and pharmaceutical technology.

The main aim of the Special Issue on “Biopolymers in Drug Delivery and Regenerative Medicine” is to gather recent findings and current advances on biopolymer research for biomedical applications, particularly in regenerative medicine, wound healing, and drug delivery. Contributions to this issue can be as original research or review articles and may cover all aspects of biopolymer research, ranging from the chemical synthesis and characterization of modified biopolymers, their processing in different morphologies and hierarchical structures, as well as their assessment for biomedical uses.

Prof. Pasquale Del Gaudio
Dr. Eng. Carlos A. García-González
Dr. Ricardo Starbird
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Biopolymer
  • Drug delivery
  • Regenerative medicine
  • Wound healing
  • Biodegradation
  • Nanostructured carriers

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Type of the paper: Article

Tentative title: Preparation of pectin aerogels coated with chitosan layer: curcumin case study

Authors: Milica Pantić, Gabrijela Horvat, Željko Knez, Zoran Novak

Affiliations: Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova 17, 2000 Maribor, Slovenia


The following study describes the preparation of pectin aerogels and pectin aerogels coated with an external layer of chitosan. For the preparation of pectin aerogels coated with chitosan, a new coating procedure was developed. Since pectin and pectin aerogels are highly water soluble, a function of chitosan coating is to slow down the degradation of pectin and consequently the release of the active substances. Unlike pectin, chitosan is soluble at lower pH ranges.

The aim of the study was to thoroughly investigate the influence of the chitosan layer on the structure and function of pectin aerogels. Textural properties (N2 adsorption-desorption analysis), surface morphologies (SEM), thermal properties (TGA/DSC), and functional groups (FTIR) of prepared aerogels were determined. Results indicated that the coating procedure affected the textural properties of pectin aerogels, resulting in smaller specific surface areas of 276 m2/g, compared to 441 m2/g. However, pectin aerogels coated with chitosan still retained favourable properties for carriers of active substances.

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