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Special Issue "Biofilm Control"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 31 December 2019

Special Issue Editors

Guest Editor
Dr. Manuel V. Simões

LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Roberto Frias, s/n, 4200-465 Porto, Portugal
Website | E-Mail
Interests: antimicrobial agents; emerging antimicrobial strategies; antimicrobial resistance; biofilms
Guest Editor
Dr. Sérgio F. Sousa

UCIBIO/REQUIMTE, BioSIM - Departamento de BioMedicina,Faculdade de Medicina da Universidade do Porto, Porto, Portugal
Website | E-Mail
Interests: the catalytic power of enzymes; computer-aided drug design; biofilm inhibition; biodesulfurization; computational methods in chemistry and biochemistry; metalloenzymes; biological membranes; docking and virtual screening; computational enzymatic catalysis
Guest Editor
Assist. Prof. Dr. Efstathios Giaouris

Department of Food Science and Nutrition, Faculty of the Environment, University of the Aegean, Metropolite Ioakeim 2, Myrina 81400, Lemnos, Greece
Website | E-Mail
Interests: food microbiology; food safety; foodborne pathogenic bacteria; biofilms; novel antimicrobials, disinfection; quorum sensing

Special Issue Information

Dear Colleagues,

During the last three decades, the scientific community has provided solid evidence that the concept of microbial development, organization, and evolution as communities comprises the existence of self-organization and cooperativity among cells as a driving force in community development, rather than the classical natural selection of individual microorganisms. Such a level of microbial organization as sessile communities, also known as biofilms, provides inhabitant cells with the ability to survive in hostile environments. Biofilms are particularly critical in the medical and industrial sectors. The most common practice to eliminate unwanted biofilms is the application of antimicrobial agents. However, current practices often exhibit inefficacy in biofilm control. New molecules with novel mechanisms of action are required for effective biofilm control.

Collaborations for this Special Issue are expected to provide advances on biofilm control through the prevention of biofilm formation, the use of antimicrobial agents to treat existing biofilms, and/or the development of novel strategies to disrupt the polymeric ties that bind the biofilm cells together (quorum quenchers; disruptors of extracellular polymeric substances, etc.).

Dr. Manuel V. Simões
Dr. Sérgio F. Sousa
Dr. Efstathios D. Giaouris
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Antimicrobials
  • Biofilm control
  • Medicinal chemistry
  • Pilicides
  • Quorum sensing inhibition

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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