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Extraction, Characterization, and Potential Applications of Compounds from Natural Sources

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 2163

Special Issue Editor


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Guest Editor
Laboratory for Separation Processes and Product Design, Faculty of Chemistry and Chemical Engineering, and Faculty of Mechanical Engineering, University of Maribor, Maribor, Slovenia
Interests: phase equlibria; extraction; biologically active substances; biomaterials; sub- and supercritical fluids; isolation, fractionation; chromatographic techniques; formulations; product design
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Special Issue Information

Dear Colleagues,

Lately, the demand for different types of high-quality products has increased. Substantial investigation has been concentrated on fruits and crops containing bioactive compounds. These extra nutritional constituents are present in both plant and animal products and typically occur in low quantities in foods. At this point, extraction is an important process to isolate the bioactive compounds. Both plant and animal tissues are capable of yielding a variety of bioactive extracts, which can be prepared using a vast array of extraction techniques. The biological activities of the extract highly depend on the extraction procedure, and this provides a gateway for the selection of appropriate extraction methods. A great deal of interest has been devoted to the extraction of active components from natural sources, aiming at satisfying the increasing request for natural products not only for therapeutic use but also as preventing and protecting agents. Among the large number of active substances in focus, polyphenols and fatty acids have received particular attention in the last decade. The identification and development of compounds or extracts from different tissues has become a major area of food-, health-, and medical-related research. Extracts containing these natural ingredients are incorporated into different food, therapeutic, and cosmetic products. To overcome the limitations of conventional extraction methods, novel extraction techniques can increase separation efficiency, reduce the use of raw materials, solvents, and energy, and have minimal environmental impact. In addition, the use of “green” solvents, which have numerous advantageous properties, such as being completely biodegradable, recyclable, noncorrosive, noncarcinogenic, and nonozone-depleting, enables the production of extracts that are recognized as safe and preferred by consumers.

The purpose of this Special Issue is to encourage the publication of manuscripts focused on bioactive compounds present in natural materials and processing by-products, which are of economic importance in the food, feed, and pharmaceutical industries as well as in medicine and are known for their beneficial effects.

Dr. Maša Knez Marevci
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • separation processes
  • green technologies
  • anti-microbial
  • anti-tumor
  • antioxidant
  • antimutagenic

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Published Papers (2 papers)

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Research

14 pages, 809 KiB  
Article
Genistein and Naringenin as Defense Molecules
by Sylwia Goławska, Iwona Łukasik and Paweł Czerniewicz
Molecules 2024, 29(23), 5505; https://doi.org/10.3390/molecules29235505 - 21 Nov 2024
Cited by 1 | Viewed by 681
Abstract
Genistein and naringenin, plant phenolic compounds, are recognized for their health benefits and role in plant defense against herbivores. However, little research exists on how these compounds affect aphid feeding, particularly that of the black bean aphid (Aphis fabae Scopoli) (Hemiptera: Aphididae), [...] Read more.
Genistein and naringenin, plant phenolic compounds, are recognized for their health benefits and role in plant defense against herbivores. However, little research exists on how these compounds affect aphid feeding, particularly that of the black bean aphid (Aphis fabae Scopoli) (Hemiptera: Aphididae), a major pest. This study aimed to evaluate the effects of genistein and naringenin, applied in vitro at different concentrations, on the feeding behavior of A. fabae. Statistical analysis indicated that both the type and concentration of flavonoids significantly influenced aphid stylet activity, salivation, and ingestion. Higher concentrations of both compounds hindered feeding behavior. A longer initial probe was observed on gels containing the studied flavonoids. Genistein at 0.1% completely inhibited salivation while at 0.01%, it reduced the duration of salivation activities. Both compounds also delayed the start and lengthened the duration of active ingestion, though A. fabae tolerated genistein better than naringenin. Naringenin’s effects on feeding behavior were more pronounced at higher concentrations. These findings suggest that genistein and naringenin could be valuable chemicals to protect plants from aphids in a sustainable and environmentally friendly way. Full article
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22 pages, 5400 KiB  
Article
Bioactive Properties of Microencapsulated Anthocyanins from Vaccinium floribundum and Rubus glaucus
by Carlos Barba-Ostria, Rebeca Gonzalez-Pastor, Fabián Castillo-Solís, Saskya E. Carrera-Pacheco, Orestes Lopez, Johana Zúñiga-Miranda, Alexis Debut and Linda P. Guamán
Molecules 2024, 29(23), 5504; https://doi.org/10.3390/molecules29235504 - 21 Nov 2024
Cited by 2 | Viewed by 1072
Abstract
Anthocyanins, widely recognized for their antioxidant properties and potential health benefits, are highly susceptible to degradation due to environmental factors such as light, temperature, and pH leading to reduced bioavailability and efficacy. Microencapsulation, which involves entrapment in a matrix to enhance stability and [...] Read more.
Anthocyanins, widely recognized for their antioxidant properties and potential health benefits, are highly susceptible to degradation due to environmental factors such as light, temperature, and pH leading to reduced bioavailability and efficacy. Microencapsulation, which involves entrapment in a matrix to enhance stability and bioavailability. This study aims to investigate the bioactive properties of microencapsulated anthocyanins derived from Vaccinium floribundum (Andean blueberry) and Rubus glaucus (Andean blackberry). The extracts from V. floribundum and R. glaucus were microencapsulated using maltodextrin as the carrier agent due to its film-forming properties and effectiveness in stabilizing sensitive compounds through a spray-drying process. The microcapsules were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) to assess their chemical and morphological properties. The biological activities of these microencapsulated anthocyanins were evaluated using in vitro assays for their antibacterial, antioxidant, and anti-inflammatory effects. The results indicated enhanced bioactivity of the microencapsulated anthocyanins, suggesting their potential use in developing functional foods and pharmaceuticals. This study provides valuable insights into the effectiveness of microencapsulation in preserving anthocyanins’ functional properties and enhancing their health-promoting effects, highlighting the potential for application in the food and pharmaceutical industries. Full article
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