Integrated Photonic Digital PCR Techniques

Dear Colleagues,

PCR technology has developed over several decades and through three generations due to the utilization of various techniques. As the world has recently experienced COVID-19, PCR technology has become necessary for rapid and early diagnosis. Recently, quantitative analysis has become possible with the development of a fast molecular diagnosis and digital PCR, and the expectations of molecular diagnosis have increased as ultra-fast digital PCR technology has been developed using light energy and energy conversion technologies. Photonic digital PCR is a molecular analysis technique that enables the precise quantification and amplification of DNA or RNA molecules in a sample. This method offers exceptional sensitivity and accuracy by partitioning the sample into thousands of individual reaction volumes, each containing a limited number of target molecules. Through the utilization of advanced microfluidics and optical detection systems, photonic digital PCR allows for the absolute quantification of nucleic acids without the need for a standard curve. Accordingly, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on: (1) (portable) photonic dPCR development using new technologies, (2) demonstrations using highly infectious pathogens, and (3) on-site demonstrations using portable devices.

Dr. Kyung Ho Kim
Prof. Dr. Oh-seok Kwon
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.