Adenomyosis and Endometriosis-Related Infertility
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Obstetrics and Gynecology".
Deadline for manuscript submissions: closed (20 November 2025) | Viewed by 783
Special Issue Editors
Interests: gynecology; endometriosis; fibroids; laparoscopy; hormonal therapy; hysteroscopy; ultrasonography; gynecological surgery; minimally invasive surgery; infertility
Special Issues, Collections and Topics in MDPI journals
Interests: endometrial cancer; obstetric and gynecological cancers;reproductive medicine; fertility preservation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Adenomyosis and endometriosis are significant contributors to infertility, posing considerable challenges in reproductive medicine. Adenomyosis affects fertility through multiple mechanisms, including disruption of the normal uterine architecture, impaired uterine contractility, altered local inflammatory responses, and disturbances in endometrial receptivity. These changes may impede embryo implantation and increase the risk of miscarriage. Endometriosis contributes to infertility via several pathways. The presence of ectopic endometrial tissue induces chronic inflammation, adhesions, and the anatomical distortion of pelvic structures, negatively impacting gamete transport and ovarian function. Moreover, endometriosis may diminish the ovarian reserve, negatively influence oocyte quality, and compromise embryo implantation due to altered endometrial receptivity mediated by pro-inflammatory cytokines and growth factors.
This Special Issue aims to provide an overview on endometriosis and adenomyosis-related infertility.
Treatment strategies for infertility associated with adenomyosis and endometriosis include medical management to reduce inflammation and surgical intervention to restore pelvic anatomy. Assisted reproductive technologies (ARTs), such as in vitro fertilization (IVF), are often recommended when conservative approaches fail or when anatomical distortions significantly impact reproductive potential. Evidence suggests that a multidisciplinary approach integrating surgical, medical, and ART modalities provides the most effective management to optimize fertility outcomes in patients with adenomyosis and endometriosis.
All types of manuscripts are welcome, including original research articles and reviews (narrative and systematic with/without meta-analysis).
Prof. Dr. Simone Ferrero
Dr. Giuseppe Gullo
Guest Editors
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Keywords
- endometriosis
- adenomyosis
- infertility
- in vitro fertilization
- surgery
- laparoscopy
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