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Hormone Therapies for Women
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Hormone Therapies for Women

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Sex, Gender and Hormone Based Medicine".

Deadline for manuscript submissions: 20 June 2025 | Viewed by 5795

Special Issue Editors

Dr. Giuseppe Gullo

E-Mail Website
Guest Editor
Obstetrics and Gynecology Unit, Villa Sofia Cervello Hospital, I.V.F. Public Center, University of Palermo, Via Trabucco, 180, 90146 Palermo, Italy
Interests: endometrial cancer; obstetric and gynecological cancers;reproductive medicine; fertility preservation
Special Issues, Collections and Topics in MDPI journals
Dr. Gaspare Cucinella

E-Mail Website
Guest Editor
Department Obstetrics and Gynecology, Aoor Villa Sofia Cervello, University of Palermo, Palermo, Italy
Interests: endoscopy; cancer; laparoscopy; fertility preservation; medical therapies
Special Issues, Collections and Topics in MDPI journals
Dr. Giovanni Buzzaccarini

E-Mail Website
Guest Editor
Department of Obstetrics and Gynaecology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 58-60, 20132, Milan, Italy
Interests: infertility; IVF; ART; oocyte cryopreservation; embryo transfer; endometriosis; cosmetic gynecology; hyaluronic acid; dyspareunia; vulvodynia
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Infertility is a detrimental condition that strongly affects couples, and it is expected to become more frequent worldwide. Different conditions, for both male and female partners, are responsible for infertility, accounting for structural diseases or more subtle and complex events. With this in mind, hormonal assessments play a key role in an infertility diagnosis, since their imbalance could be responsible for different outcomes. Moreover, gonadotropin administration is one of the leading medical treatments in assisted reproductive techniques (ARTs). In particular, the IVF/ICSI and IUI treatments require hormonal-controlled ovarian stimulation. In addition, new insights and proposals are provided regarding adjuvant therapies. In this scenario, we propose this Special Issue, which has the aim of moving the endocrinology field, addressing female and male infertility, forward. In particular, we aim to address two specific issues: PCOS and hypogonadotropic hypopituarism. We consider them of paramount importance, although they are often considered to be of secondary importance when dealing with IVF/ICSI procedures. Targeting this peculiar area of interest could increase both ART outcomes and the achievement of spontaneous pregnancy.

We are also grateful to receive papers with a gender approach, as well as those on the potential impacts of COVID-19 on fertility.

We would be grateful to receive original clinical and basic research articles, meta-analyses, and systematic reviews regarding the following topics:

1) PCOS and its impact on female infertility.

2) Hypogonadotropic hypopituarism diagnosis and therapy.

3) Hormone therapy and infertility.

4) Contraception.

5) Stem cells.

6) Gender medicine.

7) Medico-legal implications.

8) COVID-19 and hormones.

With the hope to have your contribution to help this field move forward,

Our best regards,

Dr. Giuseppe Gullo
Dr. Gaspare Cucinella
Dr. Giovanni Buzzaccarini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • reproductive medicine
  • hormone therapy
  • PCOS
  • gender medicine
  • contraception
  • medico-legal implications
  • inositol therapy
  • fertility preservation
  • psychological factors

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Published Papers (2 papers)

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19 pages, 1184 KiB  
Article
Effectiveness of Psychological Counseling Intervention in High-Risk Pregnancies in Italy
by Sofia Burgio, Gaspare Cucinella, Antonio Perino, Giovanni Baglio, Laura Crifasi, Robert Krysiak, Karolina Kowalcze and Giuseppe Gullo
J. Pers. Med. 2024, 14(9), 976; https://doi.org/10.3390/jpm14090976 - 15 Sep 2024
Cited by 4 | Viewed by 1122
Abstract
Background: The longitudinal study examines the effectiveness of a psychological support treatment for high-risk pregnancies using a between-groups design. It assesses the treatment’s impact on depression and fear of COVID-19 at three time points, and on prenatal attachment between the 20th and 24th [...] Read more.
Background: The longitudinal study examines the effectiveness of a psychological support treatment for high-risk pregnancies using a between-groups design. It assesses the treatment’s impact on depression and fear of COVID-19 at three time points, and on prenatal attachment between the 20th and 24th weeks of gestation (T0), postnatal attachment 15–20 days after birth (T1), and three months after birth (T2). Additionally, the study evaluates the treatment’s effectiveness on PTSD related to childbirth and parental distress at T1 and T2. Methods: The study involved 117 parents experiencing high-risk pregnancies from a Sicilian hospital: 84 mothers (40 in the experimental group, 44 in the control group) and 33 fathers (19 in the experimental group, 14 in the control group). Results: ANOVA results showed that the psychological treatment was effective for maternal variables such as postnatal attachment and parental distress, and for paternal variables such as depression, prenatal attachment, PTSD symptoms, and parental distress (ANOVA, p < 0.05). Conclusions: The study highlights the growing evidence for providing continuous psychological support to couples with high-risk pregnancies, emphasizing that this support should extend beyond childbirth to assist families through this transition. Full article
(This article belongs to the Special Issue Hormone Therapies for Women)
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20 pages, 589 KiB  
Systematic Review
Menstrual Cycle, Glucose Control and Insulin Sensitivity in Type 1 Diabetes: A Systematic Review
by Elena Gamarra and Pierpaolo Trimboli
J. Pers. Med. 2023, 13(2), 374; https://doi.org/10.3390/jpm13020374 - 20 Feb 2023
Cited by 6 | Viewed by 3730
Abstract
The correlation between the menstrual cycle and glucose control in type 1 diabetes has been the focus of several studies since the 1920s, but a few critical aspects made it particularly challenging to reach conclusive evidence. The aim of this systematic review is [...] Read more.
The correlation between the menstrual cycle and glucose control in type 1 diabetes has been the focus of several studies since the 1920s, but a few critical aspects made it particularly challenging to reach conclusive evidence. The aim of this systematic review is to reveal more solid information about the impact of the menstrual cycle on glycaemic outcomes and insulin sensitivity in type 1 diabetes and highlight the less researched areas. The literature was searched by two authors independently using PubMed/MEDLINE, Embase and Scopus (last search on 2 November 2022). The retrieved data did not allow us to perform a meta-analysis. We included 14 studies published between 1990 and 2022, with sample sizes from 4 to 124 patients. We found a wide heterogeneity in the definition of the menstrual cycle phases, glucose metrics, techniques for determining insulin sensitivity, hormonal assessment and other interfering factors considered, with an overall high risk of bias. There is no conclusive evidence, and published data do not allow us to achieve quantitative results. In a subset of patients, a possible worsening of insulin sensitivity and hyperglycaemia in the luteal phase could be observed. From the clinical standpoint, a cautious strategy based on patient-specific patterns can be considered until new, solid evidence is obtained. Full article
(This article belongs to the Special Issue Hormone Therapies for Women)
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