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Multifunctional Magnetic Hybrid Nanomaterials for Theranostic Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 6040

Special Issue Editor


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Guest Editor
Section for Applied & Environmental Physics, Dept. of Physics, Aristotle University of Thessaloniki, Thessaloniki, Greece
Interests: magnetic nanoparticles for biomedical applications (magnetic particle hyperthermia, MRI contrast agents, and magneto-mechanical cell stress); novel intermetallics for permanent magnet applications; ionic conductors for Li batteries applications

Special Issue Information

Dear Colleague,

Magnetic hybrid nanoaterials (MHN) combine different magnetic properties (ferromagnetism, exchange bias, exchange coupling, superparamagnetism, weak ferromagnetism, dipole interactions, and anistotropy) with optical (photonic and plasmonic), electrical (multiferroic and magnetoresistive), thermal (thermosensitive), mechanical (force exertion and magnetostrictive), chemical (organic/inorganic and polymeric) properties in heterodimer, core-shell, polymer or liposome encapsulated, chemically functionalized and bioconjugated 1D, and 2D and 3D nanostructured entities (quantum dots, nanotubes, nanowires, nanorods, chains, dumbbells, dendrimers, nanoparticles, nanoclusters, nanocomposites, nanoporous materials, and carbon-based nanostructures).

Because of the negligible magnetic susceptibility of the biological samples, the unique property of MHNs to be remotely monitored by external magnetic fields, and their ability to combine and alter different physical properties in a tunable manner upon interacting with the respective analyte, based on their size and spatial arrangement, they are ideal candidates for the development of next generation theranostic applications, combining two or more theranostic functions such as genetic engineering, cell separation, cell signaling, gene delivery and gene therapy, contrast agents in magnetic resonance imaging, magnetic particle imaging, tissue engineering, site-specific drug delivery, magnetic particle hyperthermia, molecular imaging, biosensors, magneto-mechanical cell actuation, magnetoacoustic imaging, magnetophotothermal therapy, and beyond.  

This Special Issue is devoted to magnetic hybride nanomaterials, where specific nanostructural features, magnetic properties, and the combination of different physical properties are keys for any theranostic application.

Potential topics include, but are not limited to, the following:

  • multifunctional nanostructured magnetic hybrid materials
  • novel synthetic routes
  • chemical functionalization
  • bioconjugation
  • nanostructural characterization
  • magnetic properties
  • combined electrical, optical, photonic, plasmonic, thermal, mechanical, and chemical properties

Prof. Orestis Kalogirou
Guest Editor

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Keywords

  • magnetic hybrid nanomaterials
  • nanomagnetism
  • nanostructural characterization schemes
  • combinatory properties
  • multimodal diagnosis
  • cancer therapy
  • theranostics

Published Papers (2 papers)

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Research

15 pages, 2224 KiB  
Article
Diverse Surface Chemistry of Cobalt Ferrite Nanoparticles to Optimize Copper(II) Removal from Aqueous Media
by Kosmas Vamvakidis, Theodora-Marianna Kostitsi, Antonis Makridis and Catherine Dendrinou-Samara
Materials 2020, 13(7), 1537; https://doi.org/10.3390/ma13071537 - 27 Mar 2020
Cited by 13 | Viewed by 2339
Abstract
Water pollution by heavy metals is one of the most serious worldwide environmental issues. With a focus on copper(II) ions and copper complex removal, in the present study, ultra-small primary CoFe2O4 magnetic nanoparticles (MNPs) coated with octadecylamine (ODA) of adequate [...] Read more.
Water pollution by heavy metals is one of the most serious worldwide environmental issues. With a focus on copper(II) ions and copper complex removal, in the present study, ultra-small primary CoFe2O4 magnetic nanoparticles (MNPs) coated with octadecylamine (ODA) of adequate magnetization were solvothermally prepared. The surface modification of the initial MNPs was adapted via three different chemical approaches based on amine and/or carboxylate functional groups: (i) the deposition of polyethylimide (PEI), (ii) covalent binding with diethylenetriaminepentaacetic acid (DTPA), and (iii) conjugation with both PEI and DTPA, respectively. FT-IR, TGA, and DLS measurements confirmed that PEI or/and DTPA were successfully functionalized. The percentage of the free amine (−NH2) groups was also estimated. Increased magnetization values were found in case of PEI and DTPA-modified MNPs that stemmed from the adsorbed amine or oxygen ligands. Comparative UV–Vis studies for copper(II) ion removal from aqueous solutions were conducted, and the effect of time on the adsorption capacity was analyzed. The PEI-modified particles exhibited the highest adsorption capacity (164.2 mg/g) for copper(II) ions and followed the pseudo-second-order kinetics, while the polynuclear copper(II) complex Cux(DTPA)y was also able to be immobilized. The nanoadsorbents were quickly isolated from the solution by magnetic separation and regenerated easily by acidic treatment. Full article
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23 pages, 4445 KiB  
Article
Graphene Oxide Based Magnetic Nanocomposites with Polymers as Effective Bisphenol–A Nanoadsorbents
by Kyriazis Rekos, Zoi-Christina Kampouraki, Charalampos Sarafidis, Victoria Samanidou and Eleni Deliyanni
Materials 2019, 12(12), 1987; https://doi.org/10.3390/ma12121987 - 20 Jun 2019
Cited by 32 | Viewed by 3434
Abstract
Magnetic graphene oxide was impregnated with polymers for the preparation of nanocomposite adsorbents to be examined for the adsorptive removal of a typical endocrine disruptor, bisphenol–A (BPA) from aqueous solutions. The polymers used were polystyrene, chitosan and polyaniline. The nanocomposites prepared were characterized [...] Read more.
Magnetic graphene oxide was impregnated with polymers for the preparation of nanocomposite adsorbents to be examined for the adsorptive removal of a typical endocrine disruptor, bisphenol–A (BPA) from aqueous solutions. The polymers used were polystyrene, chitosan and polyaniline. The nanocomposites prepared were characterized for their structure, morphology and surface chemistry. The nanocomposites presented an increase adsorptive activity for BPA at ambient conditions, compared to pure magnetic oxide, attributed to the synergistic effect of the polymers and the magnetic graphene oxide. The increased adsorption of BPA exhibited by the nanocomposites with chitosan and polyaniline could be attributed to the contribution of amine groups. Full article
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