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Special Issue "Biofunctionalization of Metallic Biomaterials"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Metals and Alloys".

Deadline for manuscript submissions: closed (20 January 2022) | Viewed by 1530

Special Issue Editors

Prof. Javier Gil
E-Mail Website
Guest Editor
Dr. Carlos Mas-Moruno
E-Mail Website
Guest Editor
Universitat Politècnica de Catalunya, Barcelona, Spain
Interests: peptides; peptidomimetics; surface functionalization; multifunctional coatings; biomaterials
Special Issues, Collections and Topics in MDPI journals
Dr. Roman Perez Antoñanzas
E-Mail Website
Guest Editor
Bioengineering Institute of Tehcnology, Universitat Internacional de Catalunya, C/ Immaculada, 22 08017 Barcelona, Spain
Interests: biomaterials; tissue engineering; bioactive ceramics; drug delivery; cell delivery; functionalization; bone regeneration
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We would like to invite you to contribute with original innovative research works to this Special Issue on “Functionalization of metallic biomaterials with bioactive peptides”. Insufficient biomaterial integration with surrounding tissues is regarded as a major cause of failure in clinical settings, which affects dental, orthopedic, and cardiovascular medical implants. To address this issue, functionalizing the material surface with molecules derived from the extracellular matrix, i.e. bioactive peptides, has been established as a feasible and promising strategy. The aim of this Special Issue is to present the latest progress and advances in the use of peptides and related molecules to functionalize and thus bioactivate metallic biomaterials, through a combination of original research papers and review articles from leading groups around the world.

In particular, topics of interest include but are not limited to the following:

  • Synthesis and development of peptidic-based coatings for material functionalization;
  • New methods and strategies of surface functionalization with peptides and related molecules;
  • Development of 2D and 3D-functionalized metallic scaffolds;
  • Metallic biomaterials (and composites) for dental, orthopedic, and cardiovascular applications;
  • In vitro and in vivo studies on the potential of functionalized metallic materials.
Prof. Javier Gil
Dr. Carlos Mas-Moruno
Prof. Roman Perez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • titanium
  • metallic biomaterials
  • peptides
  • functionalization
  • 3D scaffolds
  • coatings

Published Papers (1 paper)

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Review

Review
Mineralization of Titanium Surfaces: Biomimetic Implants
Materials 2021, 14(11), 2879; https://doi.org/10.3390/ma14112879 - 27 May 2021
Cited by 5 | Viewed by 1196
Abstract
The surface modification by the formation of apatitic compounds, such as hydroxyapatite, improves biological fixation implants at an early stage after implantation. The structure, which is identical to mineral content of human bone, has the potential to be osteoinductive and/or osteoconductive materials. These [...] Read more.
The surface modification by the formation of apatitic compounds, such as hydroxyapatite, improves biological fixation implants at an early stage after implantation. The structure, which is identical to mineral content of human bone, has the potential to be osteoinductive and/or osteoconductive materials. These calcium phosphates provoke the action of the cell signals that interact with the surface after implantation in order to quickly regenerate bone in contact with dental implants with mineral coating. A new generation of calcium phosphate coatings applied on the titanium surfaces of dental implants using laser, plasma-sprayed, laser-ablation, or electrochemical deposition processes produces that response. However, these modifications produce failures and bad responses in long-term behavior. Calcium phosphates films result in heterogeneous degradation due to the lack of crystallinity of the phosphates with a fast dissolution; conversely, the film presents cracks, which produce fractures in the coating. New thermochemical treatments have been developed to obtain biomimetic surfaces with calcium phosphate compounds that overcome the aforementioned problems. Among them, the chemical modification using biomineralization treatments has been extended to other materials, including composites, bioceramics, biopolymers, peptides, organic molecules, and other metallic materials, showing the potential for growing a calcium phosphate layer under biomimetic conditions. Full article
(This article belongs to the Special Issue Biofunctionalization of Metallic Biomaterials)
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