Special Issue "Bioactive Surfaces and Coatings for Bone Regeneration"

A special issue of Coatings (ISSN 2079-6412).

Deadline for manuscript submissions: 31 July 2019

Special Issue Editors

Guest Editor
Dr. Román Pérez

Bioengineering Institute of Technology, Universitat Internacional de Catalunya, Barcelona, Spain
Website | E-Mail
Interests: biomaterials; tissue engineering; bioactive ceramics; drug delivery; cell delivery; functionalization; bone regeneration
Guest Editor
Dr. Mireia Hoyos

Bioengineering Institute of Technology, Universitat Internacional de Catalunya, Barcelona, Spain
Website | E-Mail
Interests: biomaterials; tissue engineering; bioactive metals; antibacterial coatings; functionalization; bone regeneration; biosensing platforms
Guest Editor
Dr. Luis M. Delgado

Bioengineering Institute of Technology, Universitat Internacional de Catalunya, Barcelona, Spain
Website | E-Mail
Interests: biomaterials; tissue engineering; inflammatory response; 3D printing; biopolymers; drug delivery; macrophage polarization

Special Issue Information

Dear Colleagues,

Bone regeneration is nowadays bounded to the use of biomaterials that are able to promote tissue regeneration and to degrade after their function has been performed. These biomaterials need to be designed to attract a sufficient number of cells to the site of defect, to regulate the inflammatory response, to induce blood vessel formation, and to finally allow bone cell maturation. It is an orchestrated process that involves a series of events, which are initiated by cell–material interactions followed by cell–molecule interactions that will ultimately dictate the success of the implanted biomaterial. Once implanted, cells need to adapt to the surface of the biomaterial to stimulate the different biological processes, which are tuned by the intrinsic properties of the substrate. After the initial cell–material interaction, cells undergo a series of events in which their phenotype changes into bone tissue lineages. Furthermore, cells are continuously provided with signaling molecules that guide the final tissue regeneration.

This Special Issue focuses on the development of bone regenerative strategies based on the design of materials that provide a bioactive surface. Furthermore, the Special Issue also includes coatings that may tune the properties of the biomaterial and provide, thus, signaling molecules that are required to stimulate bone tissue regeneration.

In particular, the topics of interest include, but are not limited to:

  • Nano- and mesoporous based materials;
  • Surface functionalization strategies;
  • Molecule and/or ion releasing coatings;
  • Surface modification techniques, including etching or plasma treatment, among others;
  • Bioactive ceramic coatings on polymers and substrates.

Dr. Román Pérez
Dr. Mireia Hoyos
Dr. Luis M. Delgado
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

Open AccessArticle
Effect of Surface Pre-Treatments on the Formation and Degradation Behaviour of a Calcium Phosphate Coating on Pure Magnesium
Coatings 2019, 9(4), 259; https://doi.org/10.3390/coatings9040259
Received: 1 April 2019 / Revised: 12 April 2019 / Accepted: 15 April 2019 / Published: 18 April 2019
Cited by 1 | PDF Full-text (4511 KB) | HTML Full-text | XML Full-text
Abstract
Calcium phosphate (CaPh) coatings are considered promising surface treatments for Mg-based implants. Normally, the phase conversion process of CaPh compounds occurs during immersion in simulated body fluid (SBF) and allows the easy penetration of a corrosive medium. To solve the issue, pre-treatment is [...] Read more.
Calcium phosphate (CaPh) coatings are considered promising surface treatments for Mg-based implants. Normally, the phase conversion process of CaPh compounds occurs during immersion in simulated body fluid (SBF) and allows the easy penetration of a corrosive medium. To solve the issue, pre-treatment is often performed, creating an effective barrier that further improves the corrosion resistance of the underlying Mg. In the present work three pre-treatments including hydrothermal treatment, anodization, and plasma electrolytic oxidation (PEO) were performed on pure Mg prior to CaPh deposition. Results indicated that the composition, morphology, and thickness of the CaPh coatings were strongly influenced by the pre-treatments. Dicalcium phosphate dihydrate (DCPD) was formed on PEO surface, whilst DCPD and hydroxyapatite (HA) were deposited on hydrothermally prepared and anodized surfaces. HA could be deposited on the studied samples during immersion in SBF. The electrochemical impedance spectrum indicated that CaPh coating combined with PEO pre-treatment had the highest corrosion resistance at 120 h due to the superior barrier properties conferred by the PEO layer. Full article
(This article belongs to the Special Issue Bioactive Surfaces and Coatings for Bone Regeneration)
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