New Technological and Clinical Advances for Controlling Peri-Implantitis

Topic Information

Dear Colleagues,

This Topic highlights new basic, translational, and clinical research on factors that influence the control of peri-implantitis. It covers technologies for disease prevention, as well as surgical techniques for treatment, with a particular focus on the impact on hard and soft peri-implant tissues and the effects of disinfection. Additionally, this Topic explores the consequences of various treatment techniques on dental implants, including changes in topography, residual stresses, physical-chemical alterations to the surface, and particle detachment. Comparative analyses of these methods with other treatment approaches, along with future decontamination strategies, are also key areas of interest in this Topic.

This Topic will include original research articles and comprehensive reviews, and it is open to researchers who participated in the Symposium during the SEPA25 conference.

Prof. Dr. Javier Gil
Prof. Dr. Eugenio Velasco-Ortega
Prof. Dr. Aritza Brizuela-Velasco
Prof. Dr. Conrado Aparicio
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Journal of Functional Biomaterials jfb	5.2	6.8	2010	15.9 Days	CHF 2700	Submit
Materials materials	3.2	6.4	2008	15.2 Days	CHF 2600	Submit
Prosthesis prosthesis	4.5	4.7	2019	24.6 Days	CHF 1600	Submit
International Journal of Molecular Sciences ijms	4.9	9.0	2000	20.5 Days	CHF 2900	Submit
Oral oral	1.1	-	2021	23.3 Days	CHF 1200	Submit
Journal of Clinical Medicine jcm	2.9	5.2	2012	17.7 Days	CHF 2600	Submit

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Published Papers (2 papers)

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All JFB Materials Prosthesis IJMS Oral JCM

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15 pages, 461 KB  

Open AccessReview

Current Trends of Hyaluronic Acid Use as a Therapeutic Strategy in Peri-Implantitis: A Scoping Review

by Brigitta Bokor, Adriana Objelean and Radu Septimiu Campian

Oral 2025, 5(3), 68; https://doi.org/10.3390/oral5030068 - 5 Sep 2025

Viewed by 1311

Abstract

Peri-implantitis is marked by ongoing bone loss and soft tissue inflammation surrounding dental implants. Due to its ability to intensify tissue healing and its compatibility with the body, hyaluronic acid (HA) has appeared as a viable biomaterial for managing this oral condition. The [...] Read more.

Peri-implantitis is marked by ongoing bone loss and soft tissue inflammation surrounding dental implants. Due to its ability to intensify tissue healing and its compatibility with the body, hyaluronic acid (HA) has appeared as a viable biomaterial for managing this oral condition. The goal of this scoping review is to examine current trends and future directions for refining HA-based interventions as an adjuvant peri-implant therapy over the past decade. Using the PRISMA-ScR guidelines, a review of the literature for the past 10 years was conducted. Articles related to HA’s anti-inflammatory, antimicrobial, regenerative mechanisms were taken into consideration to underline both achievements and research related to peri-implantitis treatment management. A total of 105 articles were found, and finally, five clinical studies were included. Despite encouraging results that showed good efficacy of HA use as an adjuvant and/or preventive therapeutic agent for peri-implantitis treatment, a larger number of randomized controlled trials and standardized protocols are needed to confirm HA’s therapeutic efficacy and establish its place in routine clinical practice. Full article

(This article belongs to the Topic New Technological and Clinical Advances for Controlling Peri-Implantitis)

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19 pages, 2700 KB  

Open AccessArticle

The Influence of the Machining Drill and Direction of Rotation on the Surfaces of Ti6Al4V Dental Implants Subjected to Implantoplasty

by Esteban Padullés-Gaspar, Francisco Real-Voltas, Esteban Padullés-Roig, Miguel Punset, Guillermo Cabanes, Pablo Fernández and Javier Gil

J. Funct. Biomater. 2025, 16(6), 224; https://doi.org/10.3390/jfb16060224 - 16 Jun 2025

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Abstract

Implantoplasty is widely used to treat peri-implantitis by removing biofilms from Ti6Al4V dental implants using rotating drills. This study examined the effects of diamond and tungsten carbide drills, and rotation direction (clockwise/counterclockwise), on surface modification, corrosion behavior, and cytotoxicity. Machining was performed for [...] Read more.

Implantoplasty is widely used to treat peri-implantitis by removing biofilms from Ti6Al4V dental implants using rotating drills. This study examined the effects of diamond and tungsten carbide drills, and rotation direction (clockwise/counterclockwise), on surface modification, corrosion behavior, and cytotoxicity. Machining was performed for one minute under a controlled load. Surface roughness, nanohardness, compressive residual stress, and wettability were evaluated, along with SEM and EDX microanalyses of the residues. Corrosion behavior was evaluated using potentiostatic and potentiodynamic tests in Hank’s solution. Ion release was monitored over time, and fibroblast viability was tested using extracts at various dilutions. The higher abrasiveness of diamond drills leads to increases roughness from 0.22 mm (control) to 0.73 and 0.59 for diamond and tungsten carbide drills, respectively; in hardness from 2.2 GPa for the control to 4.8 and 3.9 GPa; and in residual compressive stress from −26 to −125 and −111 MPa, with diamond drills inducing more significant changes and producing more hydrophilic surfaces with contact angles around 54° in relation to 80° and 62° for the control and tungsten carbide, respectively. Tungsten carbide drills caused lower corrosion rates (0.0323 mm/year) than diamond drills (0.052 mm/year). In addition, we observed the presence of tungsten ion release. Cytotoxic effects on human fibroblasts were observed with both bur types, and were more pronounced with tungsten carbide, especially at lower dilutions. Only 1:10 dilutions maintained consistent cytocompatibility. The rotation direction showed no significant impact. These findings emphasize the critical influence of bur selection in implantoplasty on the biological response of surrounding tissues. Full article

(This article belongs to the Topic New Technological and Clinical Advances for Controlling Peri-Implantitis)

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