Modelling Polysaccharides-Based Hydrogels: From Preparation to Biomedical Applications

Dear Colleagues,

Hydrogels, thanks to their natural-tissue-like soft consistency and cell-loving attributes, have emerged as the most potential scaffolding substrate for three-dimensional cell culture in tissue engineering. The nature and structure of the material are essential to determine the efficiency of the scaffolds for cell spreading, proliferation, and differentiation in vivo. Among the specific scaffold requirements, interconnected open porosity is a necessary property to allow cell ingrowth and adequate vascularization, and it is also preferable that the scaffold biodegrade at a controllable rate that approximates the rate of tissue regeneration eventually creating space for new tissue growth.

This Special Issue is dedicated to the design and development of advanced customized hydrogel-based scaffolds and their applications for osteogenic/chondrogenic differentiation in vitro and in vivo.

Contributions regarding innovative materials for tissue regeneration and various aspects of their interactions with different cell types and tissues are welcome.

Prof. Domenico Russo
Prof. Luciana Sartore
Dr. Gina Lisignoli
Guest Editors

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