Dear Colleagues,

In recent years, the number of patients requiring total joint arthroplasty (TJA) and subsequent revisions is increasing due to the ageing population. Life expectancy is increasing; thus, besides premature failures, many patients are outliving their implants, which is a second concern.

Both factors lead to the prediction of a large increase in implant failure in the near future and an enormous increase in health costs. Therefore, it is necessary to develop new surfaces that will increase the longevity of implants and reduce the number of revisions.

One of the key challenges in the field of artificial joints is how to manufacture a customized artificial joint to mimic the biological counterpart in its morphology, structures, mechanics, and biology. Such a customized artificial joint must be capable of transmitting loads to the bone uniformly and within the physiological threshold.

Osseointegration is a key factor in determining bone prosthesis clinical performance. Prosthesis surface properties such as morphology, microstructure, electrical charge, surface modification, and material cytotoxicity have huge impacts on osseointegration at the interface of biocompatible materials and biosystems.

This Special Issue, “Advances in the Preparation and Application of Biocompatible Materials”, will focus on advances in the preparation and application of implant material design and development for laser additive manufacturing. Of particular interest are interfaces between biomaterials and biosystems.

It is our pleasure to invite you to submit a manuscript to this Special Issue.

Prof. Dr. Drago Dolinar
Prof. Dr. Monika Jenko
Prof. Dr. Veronika Kralj-Iglic
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• biomaterials, synthesis, and characterization
• biomaterials for implants
• dental biomaterials
• bioinspired and biomimetic materials for medical applications
• laser surface modification
• biocompatibility of implant materials
• mechanical surface modification of implant surfaces
• corundum grit blasting
• laser surface modification of implant surfaces
• interaction of cells with surfaces
• interaction of extracellular vesicles with surfaces