Dynamics of Host-Microbe Relationship

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology".

Deadline for manuscript submissions: closed (10 June 2022) | Viewed by 5090

Special Issue Editors


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Guest Editor
Drug Discoveries by Silkworm Models, Faculty of Pharma-Science, Teikyo University, Tokyo 192-0395, Japan
Interests: microbial genetics; antibiotics; probiotic; silkworms; secondary metabolism; patho-genomics; next generation sequencing

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Guest Editor
Division of infection and immunity, International Institute for Zoonosis Control, Hokkaido University, Hokkaido 060-0808, Japan
Interests: infectious diseases; antimicrobial resistance; host-pathogen interaction; anti-infective agents; pathogenicity; animal models

Special Issue Information

Dear Colleagues,

Microorganisms are distributed widely and comprise an integral part of our life. Our day-to-day life is influenced by microorganisms ranging from probiotics and commensals to disease-causing pathogenic organisms. While some microbes help strengthen the host, others are looking for opportunities to infect the host. With a lack of clear demarcation between the beneficial and pathogenic behavior of a microbe, distinguishing a friend or a foe is always challenging. To add to this challenge comes the sheer quantity and diversity of microbes within the microbiota of a single host. An understanding of how these microbes communicate and behave depending on host circumstances will allow us to operate this microbial behavior for the benefit of the host, including the treatment of infectious diseases caused by emerging and/or multi-drug resistant microorganisms.

Existing studies performed using several tools of chemical, biochemical, and omics-based approaches, including animal models, have broadened our understanding of microbial probiosis, pathogenesis, and immune response of the host. This special issue aims to deepen our understanding of microbes based on their interaction with hosts to either cause diseases or prevent and cure them. We expect to present the scientific community with a comprehensive issue that helps broaden the horizon of the dynamic host-microbe relationship by research works that have used cutting-edge next-generation tools and identified ways to exploit them for the benefit of the host. Through this special issue, we welcome contributions on issues related to the dynamics of the host-microbe relationships, including but not limited to pathogenesis of microbes in causing infectious diseases, benefits of probiotic and commensal microbiota in protecting and preventing diseases of the host by boosting immunity and beyond.

Dr. Suresh Panthee
Dr. Atmika Paudel
Guest Editors

Keywords

  • Host-microbe interaction
  • Animal model
  • Microbiome
  • Virulence
  • Antibiotics 
  • Probiotics 
  • Infectious diseases 
  • Immunity 
  • Omics-based analysis

Published Papers (1 paper)

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Review

15 pages, 1097 KiB  
Review
Environmental and Human Microbiome for Health
by Bimala Panthee, Saroj Gyawali, Pratiksha Panthee and Kuaanan Techato
Life 2022, 12(3), 456; https://doi.org/10.3390/life12030456 - 19 Mar 2022
Cited by 14 | Viewed by 4373
Abstract
Microorganisms are an essential part of life on the earth and can exist in association with virtually any living thing. The environmental microbiome is much more diverse than the human microbiome. It is reported that most microbes existing in the environment are difficult [...] Read more.
Microorganisms are an essential part of life on the earth and can exist in association with virtually any living thing. The environmental microbiome is much more diverse than the human microbiome. It is reported that most microbes existing in the environment are difficult to culture in the laboratory. Whereas both pathogenic and beneficial microbes may be prevailing in the environment, the human body can have three categories of microbes- beneficial, pathogenic, and opportunistic pathogenic. With at least 10-fold more cells than human cells, microbes as normal flora are critical for human survival. The microbes present in the human body play a crucial role in maintaining human health, and the environmental microbiome influences the human microbiome makeup. The interaction between the environmental and human microbiome highly influences human health, however it is poorly understood. In addition, as an established infection is associated with health-seeking behavior, a large number of studies have focused on the transmission and dynamics of infectious microorganisms than the noninfectious or beneficial ones. This review will summarize how the interaction between the environmental and human microbiome affects human health and identify approaches that might be beneficial for humans to improve health by being exposed to the natural environment. Full article
(This article belongs to the Special Issue Dynamics of Host-Microbe Relationship)
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