Neuroinflammation and Multiple Sclerosis: Pathogenesis to Personalized Therapy
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".
Deadline for manuscript submissions: 10 May 2026 | Viewed by 88
Special Issue Editor
Special Issue Information
Dear Colleagues,
Multiple sclerosis (MS) is a complex, immune-mediated disease of the central nervous system characterized by significant heterogeneity in its clinical presentation, progression, and response to treatment. Personalized medicine represents a promising paradigm shift in the management of multiple sclerosis, enabling the integration of biomarkers with patient-specific clinical profiles to inform more-precise and -individualized therapeutic strategies.
In recent decades, advances in immunology, genetics, and neuroimaging have significantly enriched our understanding of multiple sclerosis pathogenesis. However, translating these insights into personalized, evidence-based treatment strategies that can be effectively implemented in neurological practice remains an ongoing and pressing challenge.
This Special Issue aims to explore how insights into MS pathogenesis can inform the development of personalized approaches to diagnosis, prognosis, and therapy, ultimately improving clinical outcomes and patient quality of life. We highlight recent advances in biomarker discovery, neuroimaging, genomics, and individualized immunomodulatory strategies that pave the way toward the more-tailored and -effective management of MS.
We invite original research and reviews that address any aspect of personalized medicine in MS, including but not limited to molecular profiling, patient stratification, predictive modeling, and innovative therapeutic interventions. We welcome contributions that will advance the scientific and clinical understanding of personalized approaches in MS and contribute to the development of more-precise, mechanism-informed, and patient-centered models of care.
Dr. Alenka Horvat Ledinek
Guest Editor
Manuscript Submission Information
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Keywords
- personalized medicine
- multiple sclerosis
- neuroinflammation
- biomarkers
- patient stratification
- mechanism-based therapy
- neuroimaging
- genomic profiling
- clinical decision-making
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