Multifunctional Lipid Nanoparticles for Drug Delivery and Targeted Therapy
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Drug Delivery".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 3
Special Issue Editor
Special Issue Information
Dear Colleagues,
Lipid nanoparticles represent an established means of potent nucleic acid delivery, with demonstrated clinical success in applications including siRNA therapies and mRNA vaccines and an expanding preclinical pipeline across a wide variety of indications. As the interest in utilizing lipid nanoparticles for a broader range of applications grows, potential challenges—including limitations in targeting and toxicity—have emerged, alongside exciting new frontiers for platform development, including theragnostics and multi-drug delivery. These obstacles and opportunities have ultimately inspired the exploration of new approaches to enhance and expand lipid nanoparticle functions.
To highlight these advances, this Special Issue, “Multifunctional Lipid Nanoparticles for Drug Delivery and Targeted Therapy”, will focus on platforms that go beyond traditional delivery. Its scope covers, but is not limited to, the development of lipid nanoparticles that
- Modulate or leverage biological responses;
- Achieve the delivery of multiple cargos;
- Incorporate bio-responsive materials;
- Utilize innovative targeting strategies, including intracellular targeting;
- Include imaging or theragnostic components;
- Feature new approaches to lipid nanoparticle design.
We aim to publish work on current and emerging lipid nanoparticle systems that utilize cutting-edge strategies to enhance therapeutic delivery. By featuring a variety of approaches to improving lipid nanoparticle performance across different applications, this Special Issue will offer a comprehensive perspective on developing technologies to inform the next generation of lipid nanoparticle researchers. It is our pleasure to invite you to contribute original research articles, reviews, or communications for consideration for this exciting Special Issue.
Dr. Margaret Billingsley
Guest Editor
Manuscript Submission Information
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Keywords
- drug delivery
- bio-responsive materials
- lipid nanoparticle (LNP)
- combination therapy
- targeting
- theragnostic
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