Erectile Dysfunction in Men with Chronic Diseases: From Pathophysiology to Clinical Management

Dear Colleagues,

Advancements in medical practice have improved life expectancy in men suffering from many severe chronic diseases (e.g., HIV infection, spinal cord injury, cancer, chronic obstructive pulmonary disease). While this is of course a positive result, there are still certain aspects that require improvement. Indeed, one of the consistent complaints coming from survivors of such diseases is sexual dysfunction. Erectile dysfunction (ED) is often overlooked and insufficiently managed in patients with multiple or severe morbidities owing to many factors, including clinicians feeling too ashamed to address sexual function. ED etiology includes vascular, neurologic, endocrine, and iatrogenic causes. Chronic illnesses and/or their treatments may be involved in one or more of these etiopathogenic factors. ED represents a poor prognostic factor for health quality, life satisfaction, and quality of life, and epidemiological data have revealed that men suffering from a chronic disease are more frequently affected by sexual dysfunctions than the general population, although there is a gap in knowledge in literature on pathology and clinical management of ED for these special populations. It is for this reason that this Special Issue has been established, which will provide a thorough overview of etiopathogenesis, management, and treatment options of ED in frail men.

Dr. Settimio D'Andrea
Prof. Dr. Sandro Francavilla
Prof. Arcangelo barbonetti
Guest Editor

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