Disease Progression of Retinopathy in Type 2 Diabetes

Dear Colleagues, 

Diabetic retinopathy (DR) is a frequent complication of diabetes and through its sight-threatening complications, i. e., macular edema and proliferative retinopathy, may lead to blindness.

The availability of treatment only for the late stages of the disease and its rate of success make it urgent to understand the early alterations of DR and their progression in order to develop timely treatments before vision loss.

A fundamental characteristic of DR is that its course is not linear and the progression of DR varies in different individuals with the development of sight-threatening complications occurring only in a few patients. The activity of disease and its progression varies from patient to patient. It is clear now that only a subset of patients with diabetes who develop retinal changes is expected to progress to advanced retinopathy stages and is at risk of losing functional vision during their lifetime. This Special Issue is aimed at the importance of the identification of biomarkers of progression of DR to vision-threatening complications. In addition, this Special Issue, will emphasize the importance of retinal imaging in the diagnosis and characterization of progression of diabetic retinopathy. 

Prof. Dr. Jose Cunha-Vaz
Guest Editor

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