Special Issue "The Role of Oxidant Stress in Disease"
Deadline for manuscript submissions: closed (30 November 2016).
Interests: rare respiratory diseases; alpha-1 antitrypsin deficiency; primary ciliary dyskinesia; cystic fibrosis; idiopathic pulmonary fibrosis
Special Issues, Collections and Topics in MDPI journals
Oxidative stress refers to a condition caused by a persistent imbalance between antioxidants and oxidants, in favour of the latter. Under physiological conditions, reactive oxygen species (ROS) are constantly produced both by endogenous and exogenous sources in the organism where they are involved in physiological responses, such as signalling processes and defence mechanisms against infectious pathogens. However, its accumulation, either transitorily or chronically, leads to damage of the cellular components, producing changes in the cellular metabolism and its regulation, eventually leading to disease. Over the last 25 years, clinical and basic research has shown a relationship between oxidative stress and disease. In humans, oxidative stress is thought to be involved in the development of several diseases, such as cancer, cardiovascular and neurological diseases, rare diseases, and aging among many others. Once the implication of oxidative stress in a particular disease is demonstrated, the possibility of using antioxidant therapies in the clinical setting (both as antioxidant therapy and as prophylactics) is proposed. Therefore, the aim of these series of articles is to provide the reader with the latest knowledge on the biochemistry of oxidative stress and its role in the development of different human pathologies.
Dr. Francisco Dasí
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Oxidative stress
- reactive oxygen species
- reactive nitrogen species
- antioxidant therapies
- lipid peroxidation
- protein oxidation
- nucleic acid oxidation