Coronary Artery Disease: Recent Developments and Emerging Trends

Dear Colleagues,

In this Special Issue, we would like to invite submissions related to all topics of coronary artery disease. The understanding of atherosclerosis from endothelial dysfunction through different stages of atherosclerotic plaques and plaque rupture leading to myocardial infarction has taken a huge leap in the last decade. With the developments of noninvasive cardiovascular imaging including advanced echocardiography with ultrasound enhancing agents and accurate detection of inducible wall motion abnormality, the Doppler assessment of coronary flow velocity reserve during stress echocardiography has brought diagnostics to the patient bedside. Advancement in non-invasive anatomical imaging of coronary arteries to detect congenital coronary anomalies, and coronary artery plaque features and burden have made Cardiac CT angiography an essential triaging tool for patients with suspected coronary artery disease. The AI algorithm in detecting pathophysiological changes indicative of vascular inflammation surrounding the coronary arteries, which in spite of non-occlusive plaque disease have the potential of predicting MACE outcome, is an intriguing development that needs further exploration in routine clinical practice. Noninvasive testing for angina with non-occlusive coronary artery disease remains a huge challenge to the cardiac community. To develop entirely non-invasive testing for all ANOCA endotypes is one of our future tasks. Therefore, we encourage you to submit your manuscripts to this Special Issue, which can range from basic research to works on all diagnostic modalities (echocardiography, Cardiac CT angiography, Cardiac MRI) and invasive coronary physiological testing, to contribute to the dissemination of the latest research on risk stratification, modelling and all types of therapies that improve patients’ symptoms and outcomes via regressing or stabilizing coronary pathophysiological processes.

Prof. Dr. Attila Kardos
Dr. Tarun Mittal
Guest Editors

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