Mammographic Density: Biology and Clinical Applications

Dear Colleagues,

Mammographic density refers to the white and bright regions of a mammogram and reflects the architecture and composition of breast tissue. The last 40 years of research has clearly demonstrated that high mammographic density is both an independent risk factor for breast cancer and masks tumours on a mammogram. There is growing awareness amongst governments, health professionals, and consumers that incorporating mammographic density into patient care can improve the early detection of breast cancer.

Mammographic density is on the cusp of becoming a widespread health assessment tool used to identify the women most at risk of breast cancer in order to intervene early and reduce that risk. Recent advances have explored novel measurement approaches and risk assessment tools and identified new therapeutic targets. However, the underlying biological mechanisms that lead to high mammographic density, the casual factors behind its association with breast cancer risk, and how we can apply this knowledge to improving patient outcomes is still being uncovered.

In this Special Issue, we are calling for manuscripts that will help advance our understanding of mammographic density to improve the detection and prevention of breast cancer. We invite original research articles, reviews, and current opinions on all aspects of mammographic density including biology, epidemiology, and clinical medicine.

Assoc. Prof. Wendy Ingman
Dr. Kara Britt
Dr. Pallave Dasari
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.