Special Issue "Cystic and Non-Cystic, Fibrosis Bronchiectasis: Drifting from Molecular to Clinical Practice"
Deadline for manuscript submissions: 25 December 2019
Dr. Natália Martins
Faculty of Medicine, University of Porto – Portugal; Institute for Research and Inovation in Health (i3S), University of Porto - Portugal
Interests: evidence-based medicine; phytochemistry; phytopharmacology; drug discovery; natural products biochemistry; bioactive molecules; functional foods; nutraceuticals
In recent years, there has been increasing attention to non-cystic fibrosis (CF) bronchiectasis. For CF, the large number of studies performed in this area has led to a significant improvement in the overall life expectancy and quality of life of these patients, by using increasingly specific and effective therapeutic strategies. These advances, by allowing young patients to live longer and with better quality of life, present challenges to adulthood intervention.
On the other hand, non-CF bronchiectasis has been conceived of as one of the most neglected diseases in respiratory medicine. In fact, few studies have been done on this subject, so there is an urgent need to deepen our knowledge and address this complex chronic condition. In addition, the incidence of non-CF bronchiectasis is more frequent than what clinicians expected. Indeed, according to epidemiological data, a marked raise in bronchiectasis’ all-cause morbimortality has been stated, mainly due to multiple and recurrent exacerbations, triggered by complex infectious statuses and other complications. Thus, considering this scenario, there is an urgent need to carry out studies that allow us to more clearly understand the following: (1) the etiology underlying each case, since there is still a large percentage of patients considered idiopathic, and (2) the mechanisms associated with chronic infection and repetitive exacerbations, in order to find more effective strategies to combat them.
In this sense, all submissions addressing all of the above highlighted aspects on CF and non-CF bronchiectasis are welcome to this Special Issue. Thus, original articles, comprehensive and critical reviews, case reports, and even letters are of utmost interest, given the expansive scope of this area.
Dr. Adelina Amorim
Dr. Margarida Redondo
Dr. David Araújo
Dr. Natália Martins
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.
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- Cystic fibrosis
- Chronic infections
- Quality of life
- Therapeutic strategies
- Pulmonary rehabilitation
- Inhaled therapy