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Clinical Advances in Orthopaedic Treatment of Lumbar and Spine Diseases: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 25 August 2025 | Viewed by 3280

Special Issue Editor

Dr. Nissim Ohana

E-Mail Website
Guest Editor
Orthopedic Department, Meir Medical Center, Kfar Saba, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 4428164, Israel
Interests: spine surgery; orthopedic surgery; lumbar spine surgery; spine diseases; osteoporotic fractures
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It was a pleasure to collaborate as a Guest Editor on the Special Issue “Clinical Advances in Orthopaedic Treatment of Lumbar and Spine Diseases” for the Journal of Clinical Medicine, which published four feature papers (https://www.mdpi.com/journal/jcm/special_issues/XBQB5V61G0). We are launching a second edition of the Special Issue, titled “Clinical Advances in Orthopaedic Treatment of Lumbar and Spine Diseases: 2nd Edition”.

The field of orthopaedic surgery is constantly evolving, driven by advancements in medical technology, surgical techniques, and our understanding of diseases and conditions affecting the lumbar spine. Lumbar spine surgery plays a pivotal role in addressing a wide range of conditions, including degenerative disc disease, spinal stenosis, herniated discs, trauma, neoplastic spine diseases and spinal deformities.

As we strive for improved patient outcomes and enhanced quality of life, it is essential to embrace and disseminate the latest clinical advances in this field.

This special issue of our journal focuses on the clinical advances in orthopaedic treatment of lumbar and spine diseases. We invite researchers, clinicians, and experts in the field to contribute their valuable insights, innovative research, and novel treatment approaches. By sharing your knowledge and experiences, we can collectively push the boundaries of our understanding and improve the standard of care for patients with lumbar spine conditions.

The topics of interest for this special issue include, but are not limited to:

  1. Minimally invasive surgical techniques for lumbar spine disorders
  2. Navigation-assisted and robotic-assisted spine surgery
  3. Biologics and regenerative therapies in the treatment of lumbar spine diseases
  4. Advances in spinal fusion techniques and implants
  5. Patient-specific approaches in the management of spinal deformities
  6. Rehabilitation and postoperative care in lumbar spine surgery
  7. Outcomes research and quality improvement initiatives in spine surgery
  8. Neurosurgical perspectives on lumbar spine surgery

We encourage authors to submit original research articles, review articles that contribute to the body of knowledge in this field. Our aim is to foster collaboration, exchange ideas, and promote the adoption of evidence-based practices in the management of lumbar and spine diseases.

Together, let us propel the field of orthopaedic surgery forward, improving patient outcomes, enhancing quality of life, and shaping the future of lumbar spine surgery. We look forward to receiving your valuable contributions.

Dr. Nissim Ohana
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lumbar spine surgery
  • spine surgery
  • robotic-assisted spine surgery
  • spinal fusion
  • minimally invasive surgical
  • spinal deformities

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Related Special Issue

Published Papers (3 papers)

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Research

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15 pages, 2113 KiB  
Article
Risk Factors for Rod Fracture at ≥L4-5 Levels Following Long-Segment Fusion for Adult Spinal Deformity: Results from Segment-Based Analysis
by Se-Jun Park, Jin-Sung Park, Chong-Suh Lee and Dong-Ho Kang
J. Clin. Med. 2025, 14(16), 5643; https://doi.org/10.3390/jcm14165643 - 9 Aug 2025
Viewed by 376
Abstract
Background/Objectives: Given the different biomechanical properties and surgical techniques between the L5-S1 and ≥L4-5 levels, it is necessary to explore RF risk factors at ≥L4-5 levels separately from the lumbosacral junction. This study aims to investigate the risk factors for rod fracture [...] Read more.
Background/Objectives: Given the different biomechanical properties and surgical techniques between the L5-S1 and ≥L4-5 levels, it is necessary to explore RF risk factors at ≥L4-5 levels separately from the lumbosacral junction. This study aims to investigate the risk factors for rod fracture (RF) occurring at ≥L4-5 levels following adult spinal deformity (ASD) surgery. RF occurrence was assessed at the segment level. Methods: Patients who underwent ≥ 5-level fusion, including the sacrum or pelvis, with a minimum follow-up of 2 years were included in this study. Presumed risk factors in terms of patient, surgical, and radiographic variables were compared between the non-RF and RF groups at the segment level. Multivariate logistic regression analysis was performed to identify independent risk factors for RF at ≥L4-5 levels. Results: A total of 318 patients (mean age, 69.3 years; 88.4% female) were included, and 1082 segments were evaluated. During the mean follow-up duration of 47.4 months, RF developed in 45 (14.2%) patients for 51 (4.7%) segments. In multivariate logistic regression analysis, several risk factors were identified, as follows: the use of perioperative teriparatide (odds ratio [OR] = 0.26, p = 0.012), operated levels (L2-3 and L3-4 vs. L4-5 level [OR = 0.45, p = 0.022; OR = 0.16, p < 0.001, respectively]), fusion methods (posterior fusion and anterior column realignment vs. posterior lumbar interbody fusion [OR = 8.04, p < 0.001; OR = 5.37, p = 0.002, respectively]), pedicle subtraction osteotomy (PSO) (OR = 3.14, p = 0.020), and number of rods (four-rod configuration vs. dual-rod fixation [OR = 0.34, p = 0.044]). Conclusions: In this study, the factors related to RF at ≥L4-5 levels included the perioperative use of teriparatide, operated levels, fusion methods, performance of PSO, and rod configuration. Considering that surgical procedures vary by each segment, our findings may help establish segment-specific preventive strategies to reduce RF at ≥L4-5 levels. Full article
(This article belongs to the Special Issue Clinical Advances in Orthopaedic Treatment of Lumbar and Spine Diseases: 2nd Edition)
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9 pages, 676 KiB  
Article
Do All Fractures in the Ankylotic Spine Really Require Surgical Intervention?
by Moshe Stavsky, Elad Harats, Ahmad Sharabati, Amjad Hamad, Harel Arzi, Bilal Qutteineh and Yair Barzilay
J. Clin. Med. 2025, 14(15), 5599; https://doi.org/10.3390/jcm14155599 - 7 Aug 2025
Viewed by 284
Abstract
Background: Patients with ankylotic spines suffering from vertebral column fractures are frequently operated on to maintain spinal stability and prevent secondary displacement and nerve damage. The aim of this study was to identify a subset of patients that may be treated non-operatively, [...] Read more.
Background: Patients with ankylotic spines suffering from vertebral column fractures are frequently operated on to maintain spinal stability and prevent secondary displacement and nerve damage. The aim of this study was to identify a subset of patients that may be treated non-operatively, thus avoiding operative complications in this group of patients. Methods: Extension-type injuries in patients with DISH (diffuse idiopathic skeletal hyperostosis) not involving the posterior elements of the spine comprised the study group. Results: Twenty two extension fractures occurred in 21 patients with DISH in SZMC (Shaare Zedek Medical Cente) between 2014–2025. All patients were treated non-operatively. Patients were allowed free mobilization, and no orthosis was used. The only limitation was keeping the bed inclined to 20–30 degrees to prevent extension at the fracture site. All fractures healed uneventfully, and no patient required late surgical intervention, and no neurological complications were noted. Conclusions: Patients with DISH who sustain extension-type injuries of the thoracolumbar spine, with no involvement of the posterior elements, may be treated non-operatively, with good results. Full article
(This article belongs to the Special Issue Clinical Advances in Orthopaedic Treatment of Lumbar and Spine Diseases: 2nd Edition)
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Review

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20 pages, 4166 KiB  
Review
Orthopedic Manifestations of Syringomyelia: A Comprehensive Review
by Mohamad Fadila, Geva Sarrabia, Shay Shapira, Eyal Yaacobi, Yuval Baruch, Itzhak Engel and Nissim Ohana
J. Clin. Med. 2025, 14(9), 3145; https://doi.org/10.3390/jcm14093145 - 1 May 2025
Cited by 1 | Viewed by 2316
Abstract
Background: Syringomyelia is a complex neurological disorder characterized by a fluid-filled cavity (syrinx) within the spinal cord, frequently resulting from altered cerebrospinal fluid (CSF) dynamics. While its clinical manifestations are diverse, orthopedic complications such as scoliosis, pes cavus, and Charcot arthropathy may [...] Read more.
Background: Syringomyelia is a complex neurological disorder characterized by a fluid-filled cavity (syrinx) within the spinal cord, frequently resulting from altered cerebrospinal fluid (CSF) dynamics. While its clinical manifestations are diverse, orthopedic complications such as scoliosis, pes cavus, and Charcot arthropathy may represent early diagnostic clues yet are often under-recognized. Methods: This comprehensive review synthesizes the current literature on the pathophysiology, clinical presentation, diagnostic strategies, and management approaches of syringomyelia, with a specific emphasis on its orthopedic manifestations. Additionally, we present a detailed case of neuropathic shoulder arthropathy associated with advanced syringomyelia. Results: Orthopedic involvement in syringomyelia includes progressive spinal deformities and neurogenic joint destruction, particularly affecting the shoulder and elbow. Scoliosis is frequently observed, especially in association with Chiari malformations, and may precede neurologic diagnosis. Charcot joints result from impaired proprioception and protective sensation. The case presented illustrates the diagnostic challenges and therapeutic dilemmas in managing advanced neuro-orthopedic complications in syringomyelia. Conclusions: Syringomyelia should be considered in the differential diagnosis of atypical musculoskeletal presentations. Early recognition and multidisciplinary management are essential to prevent irreversible orthopedic sequelae. Conservative treatment remains the mainstay in stable cases, while surgery is reserved for progressive disease. Orthopedic assessment plays a pivotal role in the diagnostic pathway and long-term care of affected patients. Full article
(This article belongs to the Special Issue Clinical Advances in Orthopaedic Treatment of Lumbar and Spine Diseases: 2nd Edition)
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