Special Issue "Frontiers in Vascular Stiffness: Part II"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Vascular Medicine".

Deadline for manuscript submissions: 20 June 2023 | Viewed by 612

Special Issue Editors

Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Interests: arteriosclerosis; arterial stiffness; cardiovascular risk
Special Issues, Collections and Topics in MDPI journals
Medicina Clinica, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy
Interests: vascular diseases; arterial stiffness; hypertension; blood pressure measurement
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The area of vascular disease research is constantly evolving. New methods and devices are able to assess the dynamic properties of vessels in a way that was not possible a few years ago. The measurement of vascular stiffness is becoming increasingly important for evaluating blood pressure profiles at multiple sites of the arterial tree in vascular ageing and in patient care. Current research is addressing and debating some unresolved technical and methodological issues in evaluating the structural and functional properties of vessels. Future progress in this area of research and the implementation of new indices and methodologies related to an increasingly reliable assessment of vascular stiffness will allow for an improvement in the early diagnosis of cardiovascular damage, and therefore, in the clinical care of patients.

After the successful contribution in this field of the first Special Issue on this topic, this second part will be open to submissions regarding new methodological advances in vascular stiffness evaluation, as well as their applications in clinical or preclinical research. A privileged space will be reserved for new clinical acquisitions regarding the relationship between non-invasive hemodynamic assessment and early vascular damage in the various fields of cardiovascular research.

Dr. Paolo Salvi
Dr. Andrea Grillo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • arterial stiffness
  • cardiovascular risk
  • early vascular damage
  • cardiovascular prevention
  • myocardial ischemia
  • arteriosclerosis

Related Special Issue

Published Papers (1 paper)

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Research

Article
Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study
J. Clin. Med. 2023, 12(6), 2123; https://doi.org/10.3390/jcm12062123 - 08 Mar 2023
Viewed by 341
Abstract
COVID-19-associated vascular disease complications are primarily associated with endothelial dysfunction; however, the consequences of disease on vascular structure and function, particularly in the long term (>7 weeks post-infection), remain unexplored. Individual pre- and post-infection changes in arterial stiffness as well as central and [...] Read more.
COVID-19-associated vascular disease complications are primarily associated with endothelial dysfunction; however, the consequences of disease on vascular structure and function, particularly in the long term (>7 weeks post-infection), remain unexplored. Individual pre- and post-infection changes in arterial stiffness as well as central and systemic hemodynamic parameters were measured in patients diagnosed with mild COVID-19. As part of in-laboratory observational studies, baseline measurements were taken up to two years before, whereas the post-infection measurements were made 2–3 months after the onset of COVID-19. We used the same measurement protocol throughout the study as well as linear and mixed-effects regression models to analyze the data. Patients (N = 32) were predominantly healthy and young (mean age ± SD: 36.6 ± 12.6). We found that various parameters of arterial stiffness and central hemodynamics—cfPWV, [email protected], and cDBP as well as DBP and MAP—responded to a mild COVID-19 disease. The magnitude of these responses was dependent on the time since the onset of COVID-19 as well as age (pregression_models ≤ 0.013). In fact, mixed-effects models predicted a clinically significant progression of vascular impairment within the period of 2–3 months following infection (change in cfPWV by +1.4 m/s, +15% in [email protected], approximately +8 mmHg in DBP, cDBP, and MAP). The results point toward the existence of a widespread and long-lasting pathological process in the vasculature following mild COVID-19 disease, with heterogeneous individual responses, some of which may be triggered by an autoimmune response to COVID-19. Full article
(This article belongs to the Special Issue Frontiers in Vascular Stiffness: Part II)
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