Special Issue "Exosomes Biogenesis, Regulation, and Function in Viral Infections"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Infectious Diseases".

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editors

Dr. Amanda Fernández Rodríguez
Guest Editor
Unit of Viral Infection and Immunity, National Center for Microbiology, Institute of Health Carlos III, Majadahonda, 28220 Madrid, Spain
Interests: transcriptomics; immunology; genetics; biomarkers; HIV; HCV; telomere; liver disease
Dr. María Ángeles Jiménez Sousa

Guest Editor
Unit of Viral Infection and Immunity, National Center for Microbiology, Institute of Health Carlos III, Majadahonda, 28220 Madrid, Spain.
Interests: HCV; HIV; infectious diseases; metabolomics; microbiome; SNPs; genetics; biomarkers; liver disease

Special Issue Information

Dear Colleagues,

During exosome biogenesis, specific molecules of cellular and pathogenic origin are selectively incorporated, including proteins, lipids, and RNAs. These molecules play an essential role in cell-to-cell communication, as exosome´s cargo can be transferred to recipient cells by endocytosis to modulate their environment.

Viral infections have evolved to exploit exosomal machinery, by incorporating specific cellular or viral factors within exosomes and transferring them to recipient cells. Thus, exosomes from infected cells can evade the host immune system as they are resistant to neutralization by antibodies and promote viral spread by infecting adjacent cells. However, the investigation into the role of exosomes in viral infections is still being elucidated.

In this Special Issue, we would like to give a comprehensive overview of the recent discoveries in exosome biogenesis, function, and regulation in viral pathogenesis. Additionally, this Special Issue also aims to identify specific viral signatures in exosomes with next-generation approaches, as this is essential for future therapeutic strategies for viral infections.

We will be grateful to receive the most relevant scientific original basic, translational, and clinical research; reviews; and meta-analysis, to provide new insights into the role of exosomes in viral infections.

Thus, exosomes have emerged as important mediators in communication in different pathophysiological processes such infectious diseases.

Dr. Amanda Fernández Rodríguez
Dr. María Ángeles Jiménez Sousa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Extracelular vesicles
  • Exosomes
  • Viral infections
  • Biomarkers

Published Papers

This special issue is now open for submission.
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