Special Issue "Exosomes Biogenesis, Regulation, and Function in Viral Infections"
Deadline for manuscript submissions: 31 December 2020.
Interests: transcriptomics; immunology; genetics; biomarkers; HIV; HCV; telomere; liver disease
Interests: HCV; HIV; infectious diseases; metabolomics; microbiome; SNPs; genetics; biomarkers; liver disease
During exosome biogenesis, specific molecules of cellular and pathogenic origin are selectively incorporated, including proteins, lipids, and RNAs. These molecules play an essential role in cell-to-cell communication, as exosome´s cargo can be transferred to recipient cells by endocytosis to modulate their environment.
Viral infections have evolved to exploit exosomal machinery, by incorporating specific cellular or viral factors within exosomes and transferring them to recipient cells. Thus, exosomes from infected cells can evade the host immune system as they are resistant to neutralization by antibodies and promote viral spread by infecting adjacent cells. However, the investigation into the role of exosomes in viral infections is still being elucidated.
In this Special Issue, we would like to give a comprehensive overview of the recent discoveries in exosome biogenesis, function, and regulation in viral pathogenesis. Additionally, this Special Issue also aims to identify specific viral signatures in exosomes with next-generation approaches, as this is essential for future therapeutic strategies for viral infections.
We will be grateful to receive the most relevant scientific original basic, translational, and clinical research; reviews; and meta-analysis, to provide new insights into the role of exosomes in viral infections.
Thus, exosomes have emerged as important mediators in communication in different pathophysiological processes such infectious diseases.
Dr. Amanda Fernández Rodríguez
Dr. María Ángeles Jiménez Sousa
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Extracelular vesicles
- Viral infections