Extracorporeal Life Support during Cardiac Arrest and Cardiogenic Shock

Dear Colleagues,

Approximately 400,000 patients experience out-of-hospital cardiac arrest (OHCA) every year in Europe and the United States. In the best emergency medical service (EMS) systems, survival with a good neurologic outcome for OHCA with refractory cardiac arrest approaches 20%. Extracorporeal life support (ECLS) during cardiopulmonary resuscitation (ECPR) sustaining oxygenated circulation until return of spontaneous circulation (ROSC) has been proposed to boost favorable outcomes. ECLS is also used to support other forms of cardiogenic shock in adults and children, such as congenital heart disease or myositis. An increasing number of centers are employing this technology in the Prehospital, Emergency Department, and Inpatient settings. To date, substantial variation in practice and outcomes have been reported, resulting in the need for significant study in this area.

The purpose of this Special Issue is to address the defining elements and outcomes, including quality, survival, and organ donation, in currently active protocols for ECPR in refractory OHCA and cardiogenic shock in adult and pediatric patients. The results may inform policy and practices for ECPR.

Dr. Lakshmi Raman
Dr. Melissa E. Brunsvold
Guest Editors

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