Same-Day Versus Non-Simultaneous Extracorporeal Membrane Oxygenation Support for In-Hospital Cardiac Arrest Complicating Acute Myocardial Infarction
Abstract
1. Introduction
2. Material and Methods
Statistical Analysis
3. Results
4. Discussion
Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
Abbreviations
AMI | acute myocardial infarction |
CI | confidence interval |
CPR | cardiopulmonary resuscitation |
ECMO | extracorporeal membrane oxygenation |
eCPR | ECMO-assisted cardiopulmonary resuscitation |
HCUP | Healthcare Cost and Utilization Project |
ICD-9CM | International Classification of Diseases-9 Clinical Modification |
ICD-10CM | International Classification of Diseases-10 Clinical Modification |
IHCA | in-hospital cardiac arrest |
NIS | National/Nationwide Inpatient Sample |
OR | odds ratio |
References
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Characteristic | Same-Day ECMO (N = 795) | Non-Simultaneous ECMO (N = 119) | p | |
---|---|---|---|---|
Age (years) | 62 (53–69) | 63 (50–67) | 0.43 | |
Female sex | 21.8 | 13.4 | 0.04 | |
Race | White | 56.2 | 60.5 | <0.001 |
Black | 5.7 | 18.5 | ||
Others a | 38.2 | 21.0 | ||
Charlson Comorbidity Index | 0–3 | 56.0 | 58.0 | 0.10 |
4–6 | 36.4 | 29.4 | ||
≥7 | 7.5 | 12.6 | ||
AMI type | STEMI | 70.6 | 68.1 | 0.59 |
NSTEMI | 29.4 | 31.9 | ||
Rhythm | Shockable | 70.2 | 83.2 | 0.003 |
Non-shockable | 29.8 | 16.8 | ||
Cardiogenic shock | 82.7 | 90.8 | 0.02 | |
Acute non-cardiac organ failure | Multiorgan | 87.2 | 95.0 | 0.01 |
Respiratory | 67.5 | 89.9 | <0.001 | |
Renal | 56.1 | 86.6 | <0.001 | |
Hepatic | 33.3 | 42.9 | 0.05 | |
Hematologic | 43.2 | 39.5 | 0.49 | |
Neurologic | 36.9 | 38.7 | 0.76 | |
Complications | VSD | 1.4 | 0.0 | 0.38 |
PMR | 0.6 | 0.0 | >0.99 | |
Hemopericardium | 1.4 | 0.0 | 0.38 | |
Cardiac tamponade | 5.5 | 0.0 | 0.004 | |
Vascular | 4.5 | 4.2 | >0.99 | |
Limb amputation | 0.0 | 5.0 | <0.001 | |
Hemorrhagic | 27.3 | 21.8 | 0.22 | |
Blood transfusion | 34.3 | 17.6 | <0.001 | |
Ischemic stroke | 9.6 | 5.0 | 0.12 | |
ICH | 2.5 | 0.0 | 0.10 | |
Non-cardiac procedures | IMV | 66.2 | 47.1 | <0.001 |
Acute hemodialysis | 5.5 | 8.4 | 0.21 | |
Bronchoscopy | 8.4 | 0.0 | <0.001 | |
Electroencephalography | 2.8 | 8.4 | 0.03 |
Characteristic | Same-Day ECMO (N = 795) | Non-Simultaneous ECMO (N = 119) | p | |
---|---|---|---|---|
In-hospital mortality | 63.1 | 44.5 | <0.001 | |
Length of stay (days) | 6 (2–14) | 7 (2–26) | 0.15 | |
Hospitalization costs (×1000 USD) | 341 (167–493) | 482 (214–1000) | <0.001 | |
Durable left ventricular assist device | 4.5 | 4.2 | >0.99 | |
Cardiac transplantation | 0.0 | 0.0 | - | |
Palliative care consultation | 16.6 | 0.0 | <0.001 | |
Do-not-resuscitate status | 15.8 | 4.2 | <0.001 | |
Discharge disposition | Home | 14.7 | 7.6 | 0.50 |
Transfer | 49.5 | 53.0 | ||
Skilled nursing facility | 21.8 | 24.2 | ||
Home with HHC | 14.0 | 15.2 | ||
Against medical advice | 14.7 | 7.6 |
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Vallabhajosyula, S.; Patlolla, S.H.; Bell, M.R.; Cheungpasitporn, W.; Stulak, J.M.; Schears, G.J.; Barsness, G.W.; Holmes, D.R. Same-Day Versus Non-Simultaneous Extracorporeal Membrane Oxygenation Support for In-Hospital Cardiac Arrest Complicating Acute Myocardial Infarction. J. Clin. Med. 2020, 9, 2613. https://doi.org/10.3390/jcm9082613
Vallabhajosyula S, Patlolla SH, Bell MR, Cheungpasitporn W, Stulak JM, Schears GJ, Barsness GW, Holmes DR. Same-Day Versus Non-Simultaneous Extracorporeal Membrane Oxygenation Support for In-Hospital Cardiac Arrest Complicating Acute Myocardial Infarction. Journal of Clinical Medicine. 2020; 9(8):2613. https://doi.org/10.3390/jcm9082613
Chicago/Turabian StyleVallabhajosyula, Saraschandra, Sri Harsha Patlolla, Malcolm R. Bell, Wisit Cheungpasitporn, John M. Stulak, Gregory J. Schears, Gregory W. Barsness, and David R. Holmes. 2020. "Same-Day Versus Non-Simultaneous Extracorporeal Membrane Oxygenation Support for In-Hospital Cardiac Arrest Complicating Acute Myocardial Infarction" Journal of Clinical Medicine 9, no. 8: 2613. https://doi.org/10.3390/jcm9082613
APA StyleVallabhajosyula, S., Patlolla, S. H., Bell, M. R., Cheungpasitporn, W., Stulak, J. M., Schears, G. J., Barsness, G. W., & Holmes, D. R. (2020). Same-Day Versus Non-Simultaneous Extracorporeal Membrane Oxygenation Support for In-Hospital Cardiac Arrest Complicating Acute Myocardial Infarction. Journal of Clinical Medicine, 9(8), 2613. https://doi.org/10.3390/jcm9082613