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Clinical Advances and Challenges in Interventional Cardiology
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Clinical Advances and Challenges in Interventional Cardiology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (20 September 2024) | Viewed by 3305

Special Issue Editor

Prof. Dr. Sung-Ho Her

E-Mail Website
Guest Editor
Department of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Interests: interventional cardiology; acute myocardial infarction; myocardial infarction; angiography; coronary angiography; atherosclerosis; vascular medicine; clinical cardiology; atrial fibrillation; hypertension
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recently, interventional cardiology has advanced in light of improvements in revascularization strategies (PCI or CABG), the treatment of structural heart disease modality (TAVR, mitral clip, etc.), and various medications. The prevalence of intravascular imaging modalities can improve the prognosis of patients at PCI. We aim to propose new insights of interventional cardiology in our innovatively changing clinical practice, including new imaging modalities and new markers and tools for prognosis and revascularization strategies or medical treatments that are developed and successfully implemented in real-world practice.

This Special Issue aims to collect a series of articles specifically related to “Clinical Advances and Challenges in Interventional Cardiology”. Therefore, interventional cardiologists are encouraged to submit their clinical studies and research as original articles or reviews to this Special Issue.

Prof. Dr. Sung-Ho Her
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • new interventional technique
  • new markers and tools
  • imaging modalities
  • treatment of structural heart disease
  • specific medications for intervention
  • complex PCI

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Review

18 pages, 3289 KiB  
Review
Clinical Outcomes of Rotational Atherectomy in the Drug-Eluting Stent Era
by Yonghee Kim, Kyusup Lee and Sung-Ho Her
J. Clin. Med. 2025, 14(7), 2199; https://doi.org/10.3390/jcm14072199 - 24 Mar 2025
Viewed by 372
Abstract
Background: The increasing prevalence of severe calcified coronary artery disease has expanded the role of rotational atherectomy (RA) in percutaneous coronary intervention (PCI). In the drug-eluting stent (DES) era, RA remains a key tool for complex lesion modification. This review focuses on [...] Read more.
Background: The increasing prevalence of severe calcified coronary artery disease has expanded the role of rotational atherectomy (RA) in percutaneous coronary intervention (PCI). In the drug-eluting stent (DES) era, RA remains a key tool for complex lesion modification. This review focuses on its clinical outcomes and evolving indications. Methods: This review was conducted as a narrative review, focusing on the most relevant clinical studies regarding RA in the DES era. Articles were identified through a systematic PubMed search. Results: Comparing to early-generation DES, new-generation DES (NG-DES) demonstrate superior outcomes due to thinner struts and biocompatible polymers. RA plays a critical role in challenging scenarios, including chronic total occlusions and de novo small vessel lesions. Despite these advances, further randomized controlled trials are needed to validate the long-term safety and efficacy of RA-based strategies. Conclusions: This review highlights the clinical outcomes of RA in the DES era and its evolving role in contemporary cardiology. RA has shown promising potential for broader clinical applications in complex coronary artery disease. However, critical knowledge gaps remain. Further research is needed to refine RA-based strategies. Full article
(This article belongs to the Special Issue Clinical Advances and Challenges in Interventional Cardiology)
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8 pages, 186 KiB  
Review
Intravascular Lithotripsy: Approach to Advanced Calcified Coronary Artery Lesions, Current Understanding, and What Could Possibly Be Studied Next
by Giorgi Kochiashvili, Natalia Fongrat, Bhavana Baraskar, Biruk Amare and Micaela Iantorno
J. Clin. Med. 2024, 13(16), 4907; https://doi.org/10.3390/jcm13164907 - 20 Aug 2024
Viewed by 2266
Abstract
Calcified and resistant narrowing of arteries poses significant difficulty in performing percutaneous coronary interventions (PCIs), as they increase the risk of subpar outcomes leading to worse clinical outcomes. Despite the existence of dedicated technologies and devices, including various balloons and atherectomy systems, they [...] Read more.
Calcified and resistant narrowing of arteries poses significant difficulty in performing percutaneous coronary interventions (PCIs), as they increase the risk of subpar outcomes leading to worse clinical outcomes. Despite the existence of dedicated technologies and devices, including various balloons and atherectomy systems, they often do not ensure sufficient plaque modification and ideal vessel preparation for optimal stent deployment. Intravascular lithotripsy (IVL), a technology originally developed for urological procedures, has recently been used to safely and selectively disrupt calcified depositions in both peripheral and coronary arteries by sonic waves that seamlessly transfer to nearby tissue, enhancing vessel compliance with minimal impact on soft tissues. In the coronary arteries, the use of IVL plays a role in the process of “vessel preparation” before the placement of stents, which is crucial for restoring blood flow in patients with severe coronary artery disease (CAD), and is considered a minimally invasive technique, reducing the need for open heart surgeries and associated risks and complications. Studies have shown that IVL can lead to improved procedural success rates and favorable long-term outcomes for patients with severely calcified coronary artery disease. With the advent of IVL, the disruption of severe calcification of coronary artery and stenotic lesions before stent implantations can be performed. Despite promising data for treating calcified lesions, IVL is significantly underutilized in clinical practice, long-term clinical data and extensive research are needed to validate its further safety and efficacy. In this article, we reviewed the literature discussing the use of IVL in the coronary arteries as an approach for addressing intravascular atherosclerotic plaques, particularly focusing on heavily calcified plaques that are resistant to standard initial PCI, while also evaluating its safety in comparison to alternative methods. Full article
(This article belongs to the Special Issue Clinical Advances and Challenges in Interventional Cardiology)
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