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Oral and Maxillofacial Surgery—Current Advances and Future Directions
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Oral and Maxillofacial Surgery—Current Advances and Future Directions

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1961

Special Issue Editors

Dr. Sung-Woon On

E-Mail Website
Guest Editor
Assistant Professor, Division of Oral and Maxillofacial Surgery, Department of Dentistry, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea
Interests: oral and maxillofacial surgery; orthognathic surgery; dental implants; magnesium alloys; temporomandibular disorder
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Byoung-Eun Yang

E-Mail Website
Guest Editor
1. Department of Oral and Maxillofacial Surgery, Hallym University Sacred Heart Hospital, Anyang 14066, Republic of Korea;
2. Department of Artificial Intelligence and Robotics in Dentistry, Graduated School of Clinical Dentistry, Hallym University, Chuncheon 24252, Republic of Korea
Interests: oral and maxillofacial surgery; tissues and regenerative medicine; dental implants; dental materials; orthognathic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The proposed Special Issue titled "Oral and Maxillofacial Surgery—Current Advances and Future Directions" aims to review the advances being made in the clinical field of oral and maxillofacial surgery and explore possible research directions for the future. We invite original or review articles on many of the latest trends in artificial intelligence, computer-assisted orthognathic surgery, static or dynamic guided implant surgery, robotic surgery, 3D printing, etc. In addition, we also welcome papers on unique variations in clinical techniques or approaches with improved results or effectiveness. Overall, this Special Issue aims to provide a comprehensive understanding of the latest clinical findings in the field of oral and maxillofacial surgery, suggesting future research directions for clinicians based on this knowledge.

Dr. Sung-Woon On
Prof. Dr. Byoung-Eun Yang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral surgery
  • artificial intelligence
  • computer-assisted surgery
  • robotic surgical procedures
  • printing
  • three-dimensional
  • dental implants
  • orthognathic surgery

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Published Papers (3 papers)

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Research

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11 pages, 6083 KiB  
Article
The Antimicrobial Effect of a Low-Frequency Square Wave Compared to Chlorhexidine
by Jin-Won Choi, Seon-Mi Byeon, Da-Hyun Lee, Pil-Young Yun and Jeong-Kui Ku
J. Clin. Med. 2025, 14(7), 2429; https://doi.org/10.3390/jcm14072429 - 2 Apr 2025
Viewed by 336
Abstract
Background/Objectives: Oral health is critical for overall health, particularly in hospitalized patients whose weakened physical state can lead to oral changes, such as dry mouth and gingivitis due to anxiety and stress. Neglected oral hygiene can lead to infections and systemic complications. [...] Read more.
Background/Objectives: Oral health is critical for overall health, particularly in hospitalized patients whose weakened physical state can lead to oral changes, such as dry mouth and gingivitis due to anxiety and stress. Neglected oral hygiene can lead to infections and systemic complications. This study aims to evaluate the antibacterial efficacy of low-frequency square-wave positive voltage electrical stimulation compared to chlorhexidine and to assess its potential as a next-generation solution for preventing hospital-acquired infections. Methods: Sixty-three tooth specimens were randomly assigned to seven groups, including various concentrations of chlorhexidine and electrical stimulation with or without brushing. Biofilm formation was induced using saliva from healthy donors and standard strains of Streptococcus mutans and Aggregatibactor actinomycetemcomitans. Bacterial colony-forming units (CFU) and absorbance changes were measured post-treatment. Results: Significant reductions in CFU counts were observed in both the chlorhexidine and electrical stimulation groups compared to the control, with the 5V2H group showing superior antibacterial efficacy over 0.12% chlorhexidine. Chlorhexidine-treated specimens demonstrated a dose-dependent response and minimal bacterial presence, while electrical stimulation showed effectiveness but with re-growth observed after 4 h. Scanning electron microscopy revealed substantial biofilm on untreated and electrically stimulated specimens, whereas chlorhexidine-treated specimens exhibited minimal bacterial presence. Conclusions: Intermittent electrical stimulation shows promise as an alternative to chlorhexidine for oral hygiene management in critical care settings, though an optimization of electrical parameters is necessary for sustained effects. This approach could reduce hospital-acquired infections by providing an effective, non-chemical method for maintaining oral hygiene. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery—Current Advances and Future Directions)
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10 pages, 3659 KiB  
Article
The Establishment of a Treatment Protocol for the Reconstruction of Mid-Sized Defects in Lip Cancer Using Combinations with the Abbe Flap
by Hyungjin Kweon, Hyunjoong Kim, Seoyeon Park, Euitae Choi, Yiqin Fang and Chunui Lee
J. Clin. Med. 2025, 14(7), 2343; https://doi.org/10.3390/jcm14072343 - 28 Mar 2025
Viewed by 320
Abstract
Background: When defects occur in the lips due to conditions such as lip cancer, it is essential to reconstruct them both functionally and aesthetically, given the vital roles that lips play in communication, nutrition, and overall appearance. Various flap techniques are available for [...] Read more.
Background: When defects occur in the lips due to conditions such as lip cancer, it is essential to reconstruct them both functionally and aesthetically, given the vital roles that lips play in communication, nutrition, and overall appearance. Various flap techniques are available for lip reconstruction, and the surgical method should be chosen based on the location and extent of the defect. Methods: This article discusses two cases of successful lip reconstruction using a combination of the Abbe flap and additional flaps, tailored to the extent of the defects. In case 1, a 52-year-old female diagnosed with angiosarcoma underwent a wide resection of 1/3 to 2/3 of her upper lip. Reconstruction was performed using an Abbe flap combined with a perialar crescentic flap. In case 2, a 54-year-old male with squamous cell carcinoma had more than 2/3 of his lower lip excised. Although the Bernard–Burrow–Webster flap is typically used for such cases, the patient was reconstructed with an Abbe flap combined with a staircase flap, addressing the limitations of traditional methods. Results: Both reconstruction surgeries achieved excellent aesthetic and functional outcomes. In case 1, the combination of the Abbe flap and perialar crescentic flap provided the patient with a natural appearance and preserved lip functionality. In case 2, the Abbe flap and staircase flap technique effectively restored lip function while avoiding complications such as microstomia and surgical scars associated with more conventional methods. Conclusions: The findings underscore that using the Abbe flap in combination with the perialar crescentic advancement flap or staircase flap can effectively restore both the functional and aesthetic integrity of the lips, particularly in cases involving significant tissue loss. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery—Current Advances and Future Directions)
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Review

Jump to: Research

15 pages, 634 KiB  
Review
Chat Generative Pre-Trained Transformer (ChatGPT) in Oral and Maxillofacial Surgery: A Narrative Review on Its Research Applications and Limitations
by Sung-Woon On, Seoung-Won Cho, Sang-Yoon Park, Ji-Won Ha, Sang-Min Yi, In-Young Park, Soo-Hwan Byun and Byoung-Eun Yang
J. Clin. Med. 2025, 14(4), 1363; https://doi.org/10.3390/jcm14041363 - 18 Feb 2025
Viewed by 992
Abstract
Objectives: This review aimed to evaluate the role of ChatGPT in original research articles within the field of oral and maxillofacial surgery (OMS), focusing on its applications, limitations, and future directions. Methods: A literature search was conducted in PubMed using predefined search [...] Read more.
Objectives: This review aimed to evaluate the role of ChatGPT in original research articles within the field of oral and maxillofacial surgery (OMS), focusing on its applications, limitations, and future directions. Methods: A literature search was conducted in PubMed using predefined search terms and Boolean operators to identify original research articles utilizing ChatGPT published up to October 2024. The selection process involved screening studies based on their relevance to OMS and ChatGPT applications, with 26 articles meeting the final inclusion criteria. Results: ChatGPT has been applied in various OMS-related domains, including clinical decision support in real and virtual scenarios, patient and practitioner education, scientific writing and referencing, and its ability to answer licensing exam questions. As a clinical decision support tool, ChatGPT demonstrated moderate accuracy (approximately 70–80%). It showed moderate to high accuracy (up to 90%) in providing patient guidance and information. However, its reliability remains inconsistent across different applications, necessitating further evaluation. Conclusions: While ChatGPT presents potential benefits in OMS, particularly in supporting clinical decisions and improving access to medical information, it should not be regarded as a substitute for clinicians and must be used as an adjunct tool. Further validation studies and technological refinements are required to enhance its reliability and effectiveness in clinical and research settings. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery—Current Advances and Future Directions)
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