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Orthopedic Surgery: Latest Advances and Perspectives
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Orthopedic Surgery: Latest Advances and Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 133

Special Issue Editor

Dr. Mitchell K. Ng

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, Maimonides Medical Center, 4802 10th Avenue, Brooklyn, NY 11219, USA
Interests: motion preservation; pain management; robotics/computer navigation; degenerative disc disease; orthobiologics; arthroplasty; trauma
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Orthopedic surgery continues to evolve rapidly, with significant advancements shaping the field. In the U.S., over a million total joint arthroplasties are performed annually, including more than 540,000 total hip arthroplasties and 1M+ total knee arthroplasties. Advances are also being made in relation to spinal surgery, with over 400,000 spinal fusion procedures being performed each year, including more than 340,000 interbody fusions. Emerging techniques and innovations are transforming patient outcomes, such as motion-preserving procedures (e.g., cervical and lumbar disc arthroplasty and laminoplasty), biologics to enhance fusion rates and slow degenerative disc disease, and novel strategies to mitigate proximal junctional kyphosis/failure. In joint arthroplasty, trends such as the anterior approach for total hip arthroplasty, robotic navigation, cementless total knee arthroplasty, and improved patellar resurfacing strategies are gaining prominence. This Special Issue aims to highlight the latest research, technological advancements, and future directions in the field of orthopedic surgery. We invite researchers and clinicians to submit their contributions on innovations shaping the future of orthopedic care.

Dr. Mitchell K. Ng
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • motion preservation
  • pain management
  • robotics/computer navigation
  • degenerative disc disease
  • orthobiologics
  • arthroplasty
  • trauma

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Published Papers (1 paper)

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Research

14 pages, 2221 KiB  
Article
Dynamic vs. Rigid: Transforming the Treatment Landscape for Multisegmental Lumbar Degeneration
by Caner Gunerbuyuk, Mehmet Yigit Akgun, Nazenin Durmus, Ege Anil Ucar, Helin Ilkay Orak, Tunc Oktenoglu, Ozkan Ates, Turgut Akgul and Ali fahir Ozer
J. Clin. Med. 2025, 14(15), 5472; https://doi.org/10.3390/jcm14155472 (registering DOI) - 4 Aug 2025
Abstract
Background: Multisegmental lumbar degenerative disease (ms-LDD) is a common condition in older adults, often requiring surgical intervention. While rigid stabilization remains the gold standard, it is associated with complications such as adjacent segment disease (ASD), higher blood loss, and longer recovery times. The [...] Read more.
Background: Multisegmental lumbar degenerative disease (ms-LDD) is a common condition in older adults, often requiring surgical intervention. While rigid stabilization remains the gold standard, it is associated with complications such as adjacent segment disease (ASD), higher blood loss, and longer recovery times. The Dynesys dynamic stabilization system offers an alternative by preserving motion while stabilizing the spine. However, data comparing Dynesys with fusion in multisegmental cases are limited. Objective: This study evaluates the clinical and radiographic outcomes of Dynesys dynamic stabilization versus rigid stabilization in the treatment of ms-LDD. Methods: A retrospective analysis was conducted on 53 patients (mean age: 62.25 ± 15.37 years) who underwent either Dynesys dynamic stabilization (n = 27) or PLIF (n = 26) for ms-LDD involving at least seven motion segments. Clinical outcomes were assessed using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), while radiological parameters such as lumbar lordosis (LL), sagittal vertical axis (SVA), and spinopelvic parameters (pelvic incidence, pelvic tilt and, sacral slope) were analyzed. A two-stage surgical approach was employed in the Dynesys group to enhance osseointegration, particularly in elderly osteoporotic patients. Results: Both groups showed significant improvements in VAS and ODI scores postoperatively (p < 0.001), with no significant differences between them. However, the Dynesys group demonstrated superior sagittal alignment correction, with a significant increase in LL (p < 0.002) and a significant decrease in SVA (p < 0.0015), whereas changes in the rigid stabilization group were not statistically significant. Additionally, the Dynesys group had fewer complications, including a lower incidence of ASD (0 vs. 6 cases). The two-stage technique facilitated improved screw osseointegration and reduced surgical risks in osteoporotic patients. Conclusions: Dynesys dynamic stabilization is an effective alternative to rigid stabilization in ms-LDD, offering comparable pain relief and functional improvement while preserving motion and reducing ASD risk. The two-stage approach enhances long-term stability, making it particularly suitable for elderly or osteoporotic patients. Further long-term studies are needed to confirm these findings. Full article
(This article belongs to the Special Issue Orthopedic Surgery: Latest Advances and Perspectives)
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