Advances in Rheumatology: From Bench to Bedside
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 15 July 2025 | Viewed by 1852
Special Issue Editor
Interests: SAPHO syndrome; adult still's disease; arthritis; synovitis
Special Issue Information
Dear Colleagues,
Inflammation is a normal physiological response against infection and tissue damage. However, in autoimmune disease, this process becomes dysregulated, leading to significant tissue and organ damage. Advancing our understanding of inflammatory physiology is essential for developing new treatment strategies for autoimmune diseases and identifying novel biomarkers of inflammation.
Recent advancements in our understanding of the inflammation pathophysiology have led to the development of molecules targeting specific pathways involved in the initiation and perpetuation of autoimmune diseases. This Special Issue will explore novel therapeutic strategies, including B-cell depletion, T-regulatory cell repletion, cell signalling inhibitors, and small molecular inhibitors.
Translational medicine transforms scientific discoveries from laboratory, clinical or population studies into new clinical tools and applications. This approach aims to improve human health by reducing disease incidence, morbidity, and mortality.
The “bench to bedside” (B2B) approach seeks to convert promising scientific findings into practical applications, facilitating disease prediction, prevention, diagnosis, and treatment. It bridges the gap between laboratory and clinical practice, translating basic experimental findings into theories, technologies, and methods. This means that translational medicine is a two-way concept, which includes the following:
- Promoting the transition from laboratory research to patient care, improving the clinical evaluation of new therapeutic strategies;
- Facilitating the feedback loop from clinical settings to laboratory research, refining and enhancing new treatments based on clinical observations and outcomes.
Dr. Matteo Colina
Guest Editor
Manuscript Submission Information
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Keywords
- autoimmune disease
- inflammation pathophysiology
- novel therapeutic strategies
- translational medicine
- bench to bedside (B2B)
- disease biomarkers
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