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Endocrine Surgery: Current Developments and Trends
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Endocrine Surgery: Current Developments and Trends

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: 30 August 2025 | Viewed by 863

Special Issue Editors

Dr. Leonardo Rossi

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Guest Editor
Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy
Interests: general surgery; endocrine surgery; oncologic surgery; minimally invasive surgery; robotic surgery
Special Issues, Collections and Topics in MDPI journals
Dr. Gabriele Materazzi

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Guest Editor
Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy
Interests: thyroid; parathyroid; adrenal gland; oncologic surgery; endocrine surgery; minimally invasive surgery; robotic surgery; parathyroid fluorescence

Special Issue Information

Dear Colleagues,

The field of endocrine surgery is actracting growing interests and undergoing dynamic advancements, shaping the landscape of contemporary medical practices.

This Special Issue encompasses a spectrum of topics, including minimally invasive and remote-access procedures, novel oncologic management trends, innovative imaging technologies and cutting-edge diagnostic tools. Surgeons are increasingly embracing precision medicine, tailoring interventions to individual patient profiles for improved efficacy and reduced invasiveness. The integration of robotics and advanced endoscopic techniques led to endearing cosmetic outcomes and enhanced patient satisfaction. Moreover, the evolving landscape of endocrine surgery addresses the importance of multidisciplinary collaboration, incorporating insights from endocrinologists, radiologists and pathologists to ensure a comprehensive but tailored patient approach.

We welcome researchers with expertise in the field of endocrine health to contribute relevant articles to this Special Issue. We welcome original article, review and meta-analysis studies to spread the knowledge about current trends and developments, providing our readers with a perspective in the ever-evolving terrain of endocrine surgery.

Dr. Leonardo Rossi
Dr. Gabriele Materazzi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thyroid
  • parathyroid
  • adrenal gland
  • minimally invasive surgery
  • remote-access surgery
  • robotic surgery
  • parathyroid fluorescence
  • adrenal fluorescence

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Published Papers (2 papers)

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11 pages, 683 KiB  
Article
Radiologist- and Surgeon-Performed Ultrasound (RSUS) Facilitates Minimally İnvasive Parathyroidectomy (MIP): Optimal Biochemical Parameters and Patient Outcomes
by Vahit Mutlu, Mahmut Arif Yuksek, Zafer Pekkolay, Zeynep Yegin, Ibrahim Halil Yildirim and Omer Uslukaya
J. Clin. Med. 2025, 14(7), 2279; https://doi.org/10.3390/jcm14072279 - 27 Mar 2025
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Abstract
Background/Objectives: The high success rate of minimally invasive parathyroidectomy (MIP) is dependent upon the correct preoperative localization of the solitary parathyroid adenoma (SPA). Various studies have focused on comparisons of radiologist-performed ultrasound (RUS) and surgeon-performed ultrasound (SUS) to increase the sensitivity rate of [...] Read more.
Background/Objectives: The high success rate of minimally invasive parathyroidectomy (MIP) is dependent upon the correct preoperative localization of the solitary parathyroid adenoma (SPA). Various studies have focused on comparisons of radiologist-performed ultrasound (RUS) and surgeon-performed ultrasound (SUS) to increase the sensitivity rate of US. However, the efficiency of radiologist- and surgeon-performed ultrasound (RSUS) before MIP has not frequently been reported. We aimed to evaluate the efficiency of RSUS in clinical practice. Methods: In total, 122 patients (107 females, 15 males, mean age: 47.62 ± 15.75 years) with SPA were enrolled in our study design. The patients underwent preoperative ultrasonography (US) and technetium-99-sestamibi scintigraphy. Patient data including demographic characteristics, levels of biochemical parameters (parathyroid hormone (PTH), total serum calcium and phosphorus levels), operation time, and length of hospital stay were recorded. Results: MIP was performed with success under local anesthesia following the accurate localization of the adenomas by RSUS. The mean operation time was 20.00 ± 3.87 min. The mean preoperative serum PTH, calcium, and phosphorus levels were 525.69 ± 1050.92 pg/mL, 11.38 ± 1.22 mg/dL, and 2.53 ± 0.60 mg/dL, respectively. The decline in the perioperative PTH and calcium levels reflecting a cure was observed on the first postoperative day. Postoperative sixth month evaluations of the PTH and calcium levels confirmed the significant decrease, reflecting the therapeutic cure. Since no complications occurred, the hospital discharge process was carried out on the same day. Conclusions: RSUS is a beneficial adjunctive tool to facilitate MIP, and it achieved satisfactory therapeutic success in all the patients. Full article
(This article belongs to the Special Issue Endocrine Surgery: Current Developments and Trends)
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8 pages, 2513 KiB  
Brief Report
Value of Neuroradiology Second Reads of CT Scans for Hyperparathyroidism
by Javier Bravo Quintana, Michael Bouvet, Jennifer Chang and Julie Bykowski
J. Clin. Med. 2025, 14(9), 2865; https://doi.org/10.3390/jcm14092865 - 22 Apr 2025
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Abstract
Background/Objectives: Parathyroidectomy is a curative procedure for primary hyperparathyroidism, and multi-phase CT is an integral part of surgical planning. While patients may be referred to centers specializing in endocrine surgery, their imaging may be performed at other facilities without the same high-volume [...] Read more.
Background/Objectives: Parathyroidectomy is a curative procedure for primary hyperparathyroidism, and multi-phase CT is an integral part of surgical planning. While patients may be referred to centers specializing in endocrine surgery, their imaging may be performed at other facilities without the same high-volume expertise. Methods: A retrospective review was performed of radiologist second reads of outside neck CT imaging in patients with hyperparathyroidism referred for surgical management. Results: The initial outside report was 59% sensitive for localization of parathyroid adenoma in the 74 patients with surgical pathologic confirmation. Second reads of the same CT scans correctly identified the parathyroid adenoma in an additional 24% of patients, for a total sensitivity of 83%. For the 23% of patients with pathologically confirmed multi-gland involvement, the initial outside report was 21% sensitive for lesion detection, and the second read of the same scans was 68% sensitive. Conclusions: Endocrine surgeons should be aware that community-based radiology interpretation of neck CT may be less sensitive than reported series from academic and high-volume practices. In the present study, interpretation via second read of outside CT scans by a neuroradiologist engaged with the endocrine surgery service line increased the sensitivity of detecting candidate lesions, both for single-gland and multi-gland involvement. While it is preferred to have preoperative imaging and interpretation within the same high-volume center as the surgeon for consistency of imaging quality, experience and communication, radiologist second reads deserve financial and service line support when that is not possible given the impact on surgical planning and patient care. Full article
(This article belongs to the Special Issue Endocrine Surgery: Current Developments and Trends)
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