Advances in Metallic Nanoparticles for Antibacterial and Antibiofilm Control

A special issue of Inorganics (ISSN 2304-6740). This special issue belongs to the section "Bioinorganic Chemistry".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 976

Special Issue Editors


E-Mail Website
Guest Editor
Medical and Pharmaceutical Biotechnology Unit, Center for Research and Assistance in Technology and Design of the State of Jalisco, A.C. (CIATEJ), Av. Normalistas No. 800 Col. Colinas de la Normal, Guadalajara C.P. 44270, Jalisco, Mexico
Interests: biogenic nanoparticles; biological activity

E-Mail Website
Guest Editor
Medical and Pharmaceutical Biotechnology Unit, Center for Research and Assistance in Technology and Design of the State of Jalisco, A.C. (CIATEJ), Av. Normalistas No. 800 Col. Colinas de la Normal, Guadalajara C.P. 44270, Jalisco, Mexico
Interests: biological synthesis; silver nanoparticles; bacterial biofilms

Special Issue Information

Dear Colleagues,

The formation of microbial biofilms is associated with challenges across various sectors, including medical devices, food processing equipment, and water distribution systems, among others. These biofilms represent a significant health risk due to their potential to cause infections. Microbial biofilms are communities of microorganisms that can develop on both living and inert surfaces. The methods traditionally employed to prevent microbial growth often prove ineffective at eradicating biofilms, potentially contributing to the development of resistance to antibiotics and antimicrobial agents.

One promising strategy for controlling biofilm formation involves the use of metallic nanoparticles, which offer advantages due to their unique properties, including shape, size and surface area.

This Special Issue aims to highlight recent advances in the field of metallic nanoparticles, focusing on their applications in antibacterial and antibiofilm strategies. We welcome contributions in the form of original research articles and concise critical reviews.

Dr. Eduardo Padilla-Camberos
Dr. Angélica Sofía González-Garibay
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Inorganics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chemical and biological synthesis of metallic nanoparticles
  • characterization and optimization of nanoparticles
  • antibiofilm activities of metallic nanoparticles
  • microbial biofilms
  • biofilm inhibition
  • prevention of biofilm formation
  • biofilms in medical devices and food equipment
  • biofilm infections

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

16 pages, 3874 KiB  
Article
Efficacy of Stenocereus queretaroensis-Derived Silver Nanoparticles Against Methicillin-Resistant Staphylococcus aureus Biofilms: Synthesis and Antibiofilm Activity
by Angélica Sofía González-Garibay, Iván Moisés Sánchez-Hernández, Ariadna Abigail Villarreal-Amézquita, Omar Ricardo Torres-González and Eduardo Padilla-Camberos
Inorganics 2025, 13(6), 178; https://doi.org/10.3390/inorganics13060178 - 24 May 2025
Viewed by 623
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for many infections, primarily due to its ability to form biofilms. Nanotechnology has recently been proposed as an alternative for controlling MRSA. In the present work, we evaluated the antimicrobial and antibiofilm activities of silver nanoparticles synthesized [...] Read more.
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for many infections, primarily due to its ability to form biofilms. Nanotechnology has recently been proposed as an alternative for controlling MRSA. In the present work, we evaluated the antimicrobial and antibiofilm activities of silver nanoparticles synthesized with Stenocereus queretaroensis peel extract (SAgNPs). The biosynthesis process was optimized using a response surface design. The results showed antimicrobial activity against MRSA bacteria, with a minimum inhibitory concentration and minimum bactericidal concentration of 0.15 and 0.31 µg/mL, respectively. SAgNPs inhibited biofilm formation in multi-well plates and Congo red agar. Molecular docking analysis revealed that the presence of quercetin, one of the chemical components of S. queretaroensis peel, forms hydrogen bonds with six interacting amino acids. This suggests that quercetin presents a stable binding to this site, which in turn suggests that the mechanism of action of SAgNPs is related to their binding to PBP2a. Therefore, these findings suggest a promising, environmentally friendly approach to combating antibiotic-resistant infections, potentially reducing the reliance on traditional antibiotics. Full article
Show Figures

Graphical abstract

Back to TopTop