Advances in Metal-Based Anticancer Drugs
A special issue of Inorganics (ISSN 2304-6740). This special issue belongs to the section "Bioinorganic Chemistry".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 147
Special Issue Editors
Interests: antimicrobial and anticancer activity; synthesis; spectral characterization; coordination compounds; tuberculosis; Trypanosoma cruzi
Special Issues, Collections and Topics in MDPI journals
Interests: coordination chemistry; inorganic medicinal chemistry; bioinorganic chemistry; structural chemistry; metal complexes; molecular docking; metals; pharmaceuticals; antibacterial and anticancer activity; molecular target
Special Issue Information
Dear Colleagues,
Platinum-based anticancer compounds have been used in chemotherapy since the 1980s. Despite the high effectiveness of these drugs, resistance and lack of selectivity are still major obstacles in treatment. Scientists have been exploring the bioinorganic chemistry field to develop new effective and less aggressive chemotherapy drugs. The motivation behind this Special Issue stems from there being plenty of inorganic molecules that can be tailored to allow different mechanisms of action in an organism. The rich reactivity of coordination compounds is due to the potential for variation in the type and number of ligands, the oxidation state of the metal centre, and the coordination geometry surrounding the metal complex. This chemical versatility is rarely obtained with purely organic molecules. Moreover, a synergistic effect can be achieved using a class of bioactive ligand. Based on this, new anticancer compounds with new mechanisms of action offer hope as possible alternatives to overcome the resistance problems found with conventional metallopharmaceuticals.
In this Special Issue, we will present a series of recent papers related to metal complexes and their applications as anticancer agents. We hope that you will submit work and research based on these topics.
Dr. Wendell Guerra
Dr. Carolina Oliveira
Guest Editors
Manuscript Submission Information
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Keywords
- cancer
- metallodrugs
- anticancer agents
- antiproliferative activity
- biomolecules
- metal complexes
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