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Stem Cell Innovations and Reproductive Biotechnologies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 January 2026

Special Issue Editor


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Guest Editor
Department of Poultry Breeding, National Research Institute of Animal Production, Balice near Kraków, 32-083 Balice, Poland
Interests: reproductive biology and biotechnology in different mammalian and avian species (especially pigs, goats, cattle, rabbits, horses, chickens and ducks); assisted reproductive technologies (ARTs), including experimental and applied embryology; intra- and interspecies somatic cell cloning by somatic cell nuclear transfer (SCNT); transgenic research; parthenogenetic activation of oocytes (methods and molecular mechanisms of oocyte activation); in vitro embryo production (IVP), including in vitro oocyte maturation (IVM), in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI) and in vitro embryo culture (IVC); stem cell research; epigenetic and molecular aspects of somatic/stem cell culture engineering; epigenetics in cell differentiation/dedifferentiation, embryogenesis and developmental biology, epigenetic modulation of nuclear donor cells (somatic cells, stem cells), SCNT-derived oocytes or cloned embryos; unveiling the transcriptomic, proteomic and epigenomic profiles in nuclear donor cell lin
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Special Issue Information

Dear Colleagues,

Thus far, miscellaneous types of stem cells have been discovered and thoroughly explored. They are represented, among others, by 1) pluripotent embryonic stem cells (ESCs); 2) multipotent fetal/adult somatic stem cells of mesenchymal or hematopoietic origin (MSCs or HSCs); and 3) induced pluripotent stem cells (iPSCs). Establishing a foundational comprehension of molecular and epigenetic plasticity, which underlies the abilities of all categories of stem cells to self-renew, perpetuate pluri- or multipotency and differentiate into specialized somatic cells, is crucial for uncovering their core transcriptomic, proteomic and epigenomic profiles.

This Special Issue provides the multi-faceted molecular basis for revealing the importance of current and coming trends in stem cell research and its potential implications to not only experimental embryology in mammals and birds, but also advanced reproductive biotechnologies, including SCNT-mediated cloning and IVF in mammals. Stem cell innovations targeted at the elaboration of transgenic or non-transgenic in vitro and in vivo models might be a pivotal stimulus for the rapid development of studies focused on increasing their applicability to medical approaches. The latter encompass specimen-specific reconstructive, regenerative and anti-aging therapies in avian and mammalian species, including humans.

Prof. Dr. Marcin Samiec
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mammals
  • birds
  • stem cell research
  • pluri-/multipotency
  • differentiation/dedifferentiation
  • assisted reproductive technologies (ARTs)
  • transgenic research
  • biomedicine

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