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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Advances in Antimicrobial Nanoparticles

edited by

Lide Arana

and

Ianire Mate

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1459 | Submission Open

Keywords: antimicrobial nanoparticles; resistant pathogens; antimicrobial resistance; lipid nanoparticles; biomimetic nanostructures; combined therapy; antimicrobial strategies

(This special issue belongs to the Section Molecular Nanoscience)

Precision Photosynthesis: Mechanisms and Applications in Controlled Environments

edited by

Jiangtao Hu

submission deadline 30 Oct 2026 | 2 articles | Viewed by 1321 | Submission Open

Keywords: controlled environment agriculture (CEA); photobioreactor; plant growth chamber; light-emitting diode (LED) spectrum; photosynthetic efficiency; acclimation; synthetic biology; metabolic engineering; high-throughput phenotyping; predictive modeling; vertical farming

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism in Pulmonary Embolism

edited by

Hugo Hyung Bok Yoo

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1297 | Submission Open

Keywords: pulmonary embolism; thrombosis; molecular mechanisms; coagulation; endothelial dysfunction; biomarkers; inflammation; fibrinolysis; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inflammatory Bowel Disease: From Genetics to Therapy

edited by Paweł Petryszyn

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1285 | Submission Open

Keywords: inflammatory bowel disease; IBD genetics; genomics and multi-omics; polygenic risk; precision medicine; therapeutic targets; disease prediction

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Role of Cytokines in Health and Diseases: Second Edition

edited by Hung-Jen Liu

submission deadline 30 Oct 2026 | 2 articles | Viewed by 1215 | Submission Open

Keywords: cytokines; immune regulation; disease management; signaling pathways; translational research; clinical applications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Molecular Therapeutics for Retinal Disease

edited by

Thomas Stax Jakobsen

submission deadline 30 Oct 2026 | 2 articles | Viewed by 1088 | Submission Open

Keywords: retinal disease; retinal degeneration; retinal gene therapy; regenerative medicine; neuroprotection; delivery vehicles; viral vectors; nanoparticles; cell therapy; anti-angiogenic therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cell Biology of Viruses

edited by

Shanhui Ren

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1059 | Submission Open

Keywords: molecular virology; cellular virology; virus–host interface; intracellular trafficking; cellular pathogenesis

(This special issue belongs to the Section Molecular Microbiology)

Advances in Lipedema: Pathophysiology, Prevention and Treatments

edited by Angelika Chachaj

submission deadline 30 Oct 2026 | Viewed by 1026 | Submission Open

Keywords: lipedema; microvascular dysfunction; inflammation; lipedema diagnosis; biomarkers; diet in lipedema; quality of life; compression therapy; liposuction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Cardiovascular Disease

edited by

Emrah İpek

and

Ömer Bedir

submission deadline 30 Oct 2026 | 2 articles | Viewed by 964 | Submission Open

Keywords: atherosclerosis; cardiopharmacogenetics; epigenetics; inflammation; omics; oxidative stress; remodelling; vascular biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Perspectives on Rare Diseases

edited by Maria del Carmen Garrido Navas

submission deadline 30 Oct 2026 | Viewed by 875 | Submission Open

Keywords: rare diseases; molecular mechanisms; genomics; multi-omics; long-read sequencing; structural variation; repeat expansions; artificial intelligence; machine learning; precision medicine; newborn screening; genotype–phenotype correlations; biomarkers; neuromuscular disorders; whole-genome sequencing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Stem Cells in Development and Regenerative Medicine: Molecular Insights

edited by

Jesus Chimal-Monroy

submission deadline 30 Oct 2026 | 1 articles | Viewed by 854 | Submission Open

Keywords: stem cells; cell differentiation; tissue regeneration; regenerative medicine; signaling pathways; gene expression

(This special issue belongs to the Section Molecular Biology)

Novel Biomarkers for Disease Prediction and Prognosis: Inflammatory, Metabolic and Composite Profiles

edited by

Recep Dokuyucu

and Mehmet Yilmaz

submission deadline 30 Oct 2026 | 1 articles | Viewed by 847 | Submission Open

Keywords: cancer biomarkers; inflammatory markers; metabolic biomarkers; composite indices; prognostic models; translational medicine; oxidative stress; precision medicine; risk stratification; clinical biochemistry

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanostructured Materials and Functional Molecules for Sustainable Applications

edited by

Giulia Rando

Maria Rosaria Plutino

and

Silvia Sfameni

submission deadline 30 Oct 2026 | 1 articles | Viewed by 844 | Submission Open

Keywords: nanostructured materials; functional molecules; molecular design; sustainable materials; carbon nanotubes (CNTs); biochar; nanocomposites; nanohybrids; surface functionalization; molecular interactions; green synthesis; advanced functional materials

(This special issue belongs to the Section Materials Science)

Molecular Techniques to Study Food Safety Challenges

edited by

María J. Andrade

and

Micaela Álvarez

submission deadline 30 Oct 2026 | Viewed by 833 | Submission Open

Keywords: food safety; hazards; foodborne pathogens; advanced microbial detection technologies; omics techniques; preventive measures

(This special issue belongs to the Section Molecular Microbiology)

Antimicrobial Peptides: Biosynthesis, Molecular Mechanisms and Biomedical Applications

edited by Carlos Minahk and

Lucía Lanza

submission deadline 30 Oct 2026 | 2 articles | Viewed by 820 | Submission Open

Keywords: antimicrobial peptides (AMPs); bacteriocins; antimicrobial resistance; ribosomally synthesized peptides; non-ribosomal peptides; mechanism of action; structure–function relationship; artificial intelligence in peptide design; peptide engineering; pharmacokinetics and pharmacodynamics

(This special issue belongs to the Section Molecular Microbiology)

Immune Response in Animals

edited by Yuxiang Song

submission deadline 30 Oct 2026 | 2 articles | Viewed by 761 | Submission Open

Keywords: animal immunology; immune homeostasis; infectious diseases; metabolic disorders; immunomodulatory agents; nanomaterial-based immunotherapy; livestock immune response

(This special issue belongs to the Section Molecular Immunology)

Neuro-Immune-Endocrine Systems: Mechanisms, Biomarkers, and Disease Implications

edited by

Grażyna Gromadzka

submission deadline 30 Oct 2026 | Viewed by 692 | Submission Open

Keywords: neuro-immune-endocrine interactions; aging; autoimmune diseases; metabolic disorders; cancer; neuropsychiatric disorders; neuroinflammation; molecular signaling; biomarkers; translational research

(This special issue belongs to the Section Molecular Neurobiology)

In Silico Drug Design and Virtual Screening: The Latest Advances

edited by

Alina Bora

and

Luminita Crisan

submission deadline 30 Oct 2026 | 1 articles | Viewed by 681 | Submission Open

Keywords: in silico drug design; drug discovery; virtual screening; CADD; artificial intelligence; machine learning; ADMET prediction; cheminformatics; drug repurposing; natural products

(This special issue belongs to the Section Molecular Informatics)

Molecular Pathology, Diagnosis and Therapeutic Strategies of Thrombotic Diseases

edited by Emanuele Valeriani

submission deadline 30 Oct 2026 | 1 articles | Viewed by 678 | Submission Open

Keywords: anticoagulants; cardiovascular diseases; diagnosis; platelet aggregation inhibitors; venous thromboembolism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

RNA Biology and Regulation, 2nd Edition

edited by

Naoyuki Kataoka

submission deadline 30 Oct 2026 | 1 articles | Viewed by 669 | Submission Open

Keywords: RNA processing; RNA transport; RNA localization; RNA editing; RNA synthesis; RNA stability; RNA modification; translation; transcription; RNA metabolism; human diseases

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pleiotropic Effects of Statins: Molecular Interactions and Therapeutic Potential in Human Diseases

edited by

Giulio Preta

submission deadline 30 Oct 2026 | 1 articles | Viewed by 645 | Submission Open

Keywords: statins; pleiotropic effects; lipid metabolism; adjuvant therapy

(This special issue belongs to the Section Molecular Pharmacology)

Artificial Intelligence in Nano- and Bio-Technology Systems: Focus on Molecular Research

edited by

Abbas Amini

submission deadline 30 Oct 2026 | Viewed by 601 | Submission Open

Keywords: artificial intelligence; nanotechnology, biotechnology; medicine; energy systems; blockchain

(This special issue belongs to the Section Molecular Nanoscience)

Nanomaterials and Regulated Cell Death Pathways: Novel Therapeutic Opportunities

edited by

Anton S. Tkachenko

submission deadline 30 Oct 2026 | Viewed by 582 | Submission Open

Keywords: apoptosis; ferroptosis; nanotherapy; nanotoxicity; necroptosis; oxidative stress; PANoptosis; pyroptosis; regulated cell death

(This special issue belongs to the Section Molecular Nanoscience)

Research Advances in Photodynamic Therapy

edited by

Samir Acherar

and

Céline Frochot

submission deadline 30 Oct 2026 | Viewed by 575 | Submission Open

Keywords: photodynamic therapy (PDT); photosensitizers and nanocarriers; targeting and molecular selectivity; photophysics and dosimetry; anticancer and antimicrobial applications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant-Derived Bioactive Compounds for Pharmacological Applications, 2nd Edition

edited by

Ilian Badjakov

and

Ivayla Dincheva

submission deadline 30 Oct 2026 | 1 articles | Viewed by 569 | Submission Open

Keywords: plant-derived bioactive compounds; pharmacological applications; antioxidant activity; anti-inflammatory agents; antimicrobial properties; neuroprotective effects; drug discovery; high-throughput screening; extraction and isolation techniques; structural characterization; CRISPR technology; genome editing; bioprocess engineering; bioreactor production; therapeutic potential; metabolite profiling

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Bioactive Molecules and Their Health Impacts: From Antioxidants to Therapeutic Potentials

edited by

Alessandro Attanzio

and

Marilena Briglia

submission deadline 30 Oct 2026 | Viewed by 506 | Submission Open

Keywords: bioactive molecules; cell signaling; redox homeostasis; mitochondrial bioenergetics; epigenetic modulation; host–microbiome crosstalk; therapeutic strategies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular and Cellular Research on Cardiac Repair and Regeneration

edited by

Francesca Pagano

and

Vittorio Picchio

submission deadline 30 Oct 2026 | Viewed by 471 | Submission Open

Keywords: cardiac repair; cardiomyocyte differentiation; cardiac fibroblast activation; cardiac fibrosis; cardiac tissue microenvironment; cardiac remodeling

(This special issue belongs to the Section Molecular Biology)

The GPR81 Receptor: Lactate as Signaling Molecule in Health and Disease

edited by

Tania Fiaschi

submission deadline 30 Oct 2026 | Viewed by 460 | Submission Open

Keywords: lactate; GPR81 receptor; signaling cascade

(This special issue belongs to the Section Molecular Biology)

Advances in Molecular Research on Candida Resistance

edited by

Angela Maione

submission deadline 30 Oct 2026 | 1 articles | Viewed by 394 | Submission Open

Keywords: Candida resistance; antifungal resistance; biofilm; drug repurposing; novel therapies; molecular mechanisms; antifungal agents; Candida albicans; Candida auris; host–pathogen interactions

(This special issue belongs to the Section Molecular Microbiology)

Venoms and Beyond: Molecular Targets, Cellular and In Vivo Effects

edited by

Yuri N. Utkin

and

R. Manjunatha Kini

submission deadline 30 Oct 2026 | Viewed by 391 | Submission Open

Keywords: animal venoms; toxins; structure; biological activity; molecular mechanisms; molecular targets

(This special issue belongs to the Section Molecular Toxicology)

The Molecular and Genetic Mechanisms of Hypercholesterolemia

edited by

Seyed Saeed Tamehri Zadeh

submission deadline 30 Oct 2026 | Viewed by 385 | Submission Open

Keywords: ASCVD; MI; CVD; CAD; PVD; ischemic stroke; Lp(a); LPA gene; Lp(a)-lowering treatments; homozygous familial hypercholesterolemia; heterozygous familial hypercholesterolemia; low-density lipoprotein; epidemiology; genetic determinants; lipid metabolism; PCSK9 inhibitors; emerging therapies

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Nanomedicine: Application of Nanostructured Biomaterials in the Biomedical Field

edited by

Yaser Dahman

submission deadline 30 Oct 2026 | Viewed by 384 | Submission Open

Keywords: nanomedicine; nanostructured biomaterials; targeted drug delivery; tissue regeneration; biosensing

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Insights into the Smallest Fullerene Nanocomposites from the Lab to Space

edited by

Quentin A. Parker

and

SeyedAbdolreza Sadjadi

submission deadline 30 Oct 2026 | Viewed by 378 | Submission Open

Keywords: fullerenes; C20; nanocomposites; molecular structure; outer space

(This special issue belongs to the Section Molecular Nanoscience)

Plant Stress Responses and Their Gene Regulatory Networks

edited by

Anamika Pandey

and

Mohd. Kamran Khan

submission deadline 30 Oct 2026 | Viewed by 374 | Submission Open

Keywords: plant stress responses; gene regulatory networks (GRNs); functional genomics; multi-omics integration; transcriptional regulation; epigenetic regulation; CRISPR/cas gene editing; abiotic and biotic stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms Underlying Plant Abiotic Stress Tolerance

edited by

Muhammad Tanveer Altaf

and

Muhammad Junaid Rao

submission deadline 30 Oct 2026 | Viewed by 363 | Submission Open

Keywords: abiotic stress (extreme temperatures, drought, salinity, submergence, heavy metals, and others); combine stresses; stress physiology; molecular biology; gene regulation; signal transduction; multi-omics approaches; plant–environment interaction; climate adaptation; crop improvement; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

The Mechanisms of Cucurbit Breeding, Cultivation and Quality Regulation

edited by Xiaotao Ding and Yongxue Zhang

submission deadline 30 Oct 2026 | Viewed by 286 | Submission Open

Keywords: omics; cultivation; breeding; quality; abiotic stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Advances in Genetic Variants Involved in Breast and Ovarian Cancer

edited by

Maria Aparecida Nagai

submission deadline 30 Oct 2026 | Viewed by 267 | Submission Open

Keywords: breast cancer; ovarian cancer; genetic variants; HBOC; genetic testing; hereditary

(This special issue belongs to the Section Molecular Genetics and Genomics)

Zebrafish Models of Human Disease: Uncovering Immunometabolic Mechanisms and Therapeutic Targets

edited by Juliana Moreira Mendonça Gomes

submission deadline 30 Oct 2026 | Viewed by 251 | Submission Open

Keywords: zebrafish; immunometabolism; metabolism; inflammation; cancer; obesity; diabetes; cardiovascular disease; MASH; disease modeling

(This special issue belongs to the Section Molecular Biology)

New Insight into the Discovery of Antiviral and Antibacterial Agents

edited by

Brankica Filipic

submission deadline 30 Oct 2026 | Viewed by 227 | Submission Open

Keywords: antiviral agents; antibacterial compounds; antimicrobial resistance; anti-virulence strategies; drug discovery

(This special issue belongs to the Section Molecular Pharmacology)

State-of-the-Art Molecular Endocrinology and Metabolism in Turkey

edited by

Gulali Aktas

submission deadline 30 Oct 2026 | Viewed by 187 | Submission Open

Keywords: molecular endocrinology; metabolic disorders; hormone signaling; multi-omics; precision medicine; diabetes and obesity; MASLD; endocrine disruptors; biomarkers; artificial intelligence in endocrinology

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Anti-Parasitic Drugs: Mechanisms, Novel Molecules and Big Data Applications

edited by

Chun-Xue Zhou

submission deadline 30 Oct 2026 | Viewed by 182 | Submission Open

Keywords: anti-parasitic drugs; novel drug discovery; mechanism of action; drug resistance; big data analysis; machine learning; parasitic infections; drug delivery; preclinical evaluation; natural products

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Biomarkers, Nutritional Status, and Immune Regulation in Gut and Lung Diseases

edited by

Andreina Bruno

submission deadline 30 Oct 2026 | Viewed by 180 | Submission Open

Keywords: immunity; immunometabolism; metabolism; adipocytokines; nutrition; microbiome; biomarkers; gut; lung; circular health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Signatures of Environmental Toxicants in One Health: Implications for Biodiversity, Animal and Human Health

edited by Leonardo Bittencourt and

Rafael R. Lima

submission deadline 30 Oct 2026 | Viewed by 169 | Submission Open

Keywords: one health; omics; environmental toxicology; ecotoxicology; anthropocene; biodiversity; molecular biomarkers; bioindicators and sentinel species; environmental biomonitoring

(This special issue belongs to the Section Molecular Toxicology)

Co-Infections in Parasitic Diseases: Molecular Mechanisms, Diagnostic Challenges, and Therapeutic Strategies

edited by

Cecilia Parodi

and Paula Gabriela Ragone

submission deadline 30 Oct 2026 | Viewed by 166 | Submission Open

Keywords: parasites; protozoan; co-infections; disease outcome; immune modulation; metagenomic analysis; diagnostic methods; treatment strategies; drug resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Plant Virus Life Cycle, Molecular Diagnosis, Virus–Host Interactions and Molecular Farming

edited by

Srividhya Venkataraman

submission deadline 30 Oct 2026 | Viewed by 158 | Submission Open

Keywords: plant viruses; molecular biology; replication; assembly; transmission; trafficking; virus–host interactions; plant defense responses; molecular diagnostics; RNA silencing structure

(This special issue belongs to the Section Molecular Plant Sciences)

Improving Antimicrobial Activity of Biopolymer-Based Films: Mechanisms, Functionalization Strategies, and Applications

edited by

Gabriela Dudek

submission deadline 30 Oct 2026 | Viewed by 153 | Submission Open

Keywords: biopolymer-based films; antimicrobial activity; functionalization strategies; bioactive compounds; nanoparticles; deep eutectic solvents; plasticizers; structure–property relationships; biodegradable materials; coatings and membranes

(This special issue belongs to the Section Materials Science)

Global Impact of Malignant Pleural Mesothelioma: Current Knowledge, Emerging Therapies and Future Perspectives

edited by Saé Muñiz-Hernández

submission deadline 30 Oct 2026 | Viewed by 131 | Submission Open

Keywords: pattern identification through AI; gene-driven mesothelioma; biomarkers; organoid models; genetic and epigenetic analysis

(This special issue belongs to the Section Molecular Oncology)

In Silico Methods of Assessing the Therapeutic Potential of Natural Substances

edited by

Radosław Zajdel

and

Anna Merecz-Sadowska

submission deadline 31 Oct 2026 | 6 articles | Viewed by 19880 | Submission Open

Keywords: in silico screening; natural products; molecular docking; computational drug discovery; QSAR modeling; molecular dynamics simulations; natural compounds; drug-target interactions; virtual screening; structure-activity relationships; computational chemistry; cheminformatics; ADMET prediction; bioinformatics; phytochemicals; machine learning in drug discovery; computer-aided drug design; pharmacophore modeling; natural therapeutics; computational pharmacology

(This special issue belongs to the Section Molecular Informatics)

Molecular Advances in Metabolic Dysfunction-Associated Steatotic Liver Disease

edited by Rifaat Safadi and Johnny Amer

submission deadline 31 Oct 2026 | 8 articles | Viewed by 15122 | Submission Open

Keywords: MASLD (metabolic dysfunction-associated steatotic liver disease); lipotoxicity; inflammation; mitochondrial dysfunction; gut–liver axis; liver–spleen axis; fibrosis biomarkers; translational hepatology; precision liver medicine; insulin resistance; molecular therapeutics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Endocrinology of Pregnancy

edited by

Georgios Valsamakis

submission deadline 31 Oct 2026 | 3 articles | Viewed by 14280 | Submission Open

Keywords: pregnancy; endocrine system; fetal development; maternal health; metabolism

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Displaying special issue 1051-1100 on page 22 of 64.

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