International Journal of Molecular Sciences

Mechanistic Studies on Microbiota–Host Interactions

edited by Min-Jin Kwak

submission deadline 30 Sep 2026 | 1 articles | Viewed by 684 | Submission Open

Keywords: microbiome; host-microbe interactions; gut-organ axis; extracellular vesicles; multi-omics; metagenomics; metabolomics; transcriptomics; barrier function

(This special issue belongs to the Section Molecular Microbiology)

Advanced In Vitro Models: Integrating the 3Rs in Translational Science

edited by Glaucia Maria Machado-Santelli

submission deadline 30 Sep 2026 | 1 articles | Viewed by 683 | Submission Open

Keywords: 3Rs principles; advanced in vitro models; molecular mechanisms; cell signaling; organoids; organ-on-chip; translational research; molecular profiling; tissue engineering; redox biology; microphysiological systems; translational research; alternative methods to animal testing; nanotechnology in biomedicine; tissue engineering; drug discovery platforms

(This special issue belongs to the Section Molecular Biology)

Molecular and Immunological Mechanisms Associated with Exercise

edited by

Sebastian Del Rosso

submission deadline 30 Sep 2026 | Viewed by 653 | Submission Open

Keywords: signaling pathways; exercise training adaptation; exercise and mitochondrial health; skeletal muscle secretome; exercise and extracellular vesicles; myokines; exerkines; molecular immune responses to exercise

(This special issue belongs to the Section Molecular Biology)

Molecular and Biotechnological Approaches for Enhancing Stress Resistance in Plants

edited by

Muhammad Umair Yasin

, Maozhi Ren and

Xiumei Luo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 639 | Submission Open

Keywords: plant stress resistance; molecular mechanisms; abiotic stress; biotic stress; plant biotechnology; omics technologies; gene regulation; stress signaling pathways; crop resilience; plant–microbe interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Biology of Gynecological Cancers

edited by

Kuo-Hu Chen

submission deadline 30 Sep 2026 | 1 articles | Viewed by 635 | Submission Open

Keywords: gynecologic cancer; tumor marker; ovarian cancer; endometrial cancer; uterine cancer; cervical cancer; chemotherapy; radiotherapy; target therapy; immune therapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Diagnosis of Bacterial Infections and Antimicrobial Resistance

edited by

Murat Aral

submission deadline 30 Sep 2026 | 1 articles | Viewed by 633 | Submission Open

Keywords: molecular diagnostics; bacterial infections; PCR; real-time PCR; digital PCR; next-generation sequencing; antimicrobial resistance; multiplex assays; metagenomics; point-of-care testing; assay validation; MIQE guidelines

(This special issue belongs to the Section Molecular Microbiology)

Advances in Neuroscience of Mental Disorders: Neuropsychological, Neurobiological and Neuromolecular Perspectives

edited by

Phakkharawat Sittiprapaporn

submission deadline 30 Sep 2026 | Viewed by 619 | Submission Open

Keywords: mental health; mental disorders; neurosciences; neurobiological markers

(This special issue belongs to the Section Molecular Neurobiology)

Novel Nanostructured Systems for the Formulation of Anticancer Compounds

edited by

Norbert Varga

submission deadline 30 Sep 2026 | 1 articles | Viewed by 601 | Submission Open

Keywords: encapsulation of anticancer drugs; polymer-based drug delivery systems; lipid-based drug delivery systems; protein-based drug delivery systems; determination of release kinetic parameters; dissolution studies; physicochemical characterization of drug carriers

(This special issue belongs to the Section Molecular Nanoscience)

Protein Structure, Dynamics and Interactions

edited by

Gyula Batta

and

Orsolya Tőke

submission deadline 30 Sep 2026 | 1 articles | Viewed by 594 | Submission Open

Keywords: protein; structure; folding; dynamics; interactions; NMR; X-ray crystallography; cryo-electron microscopy; AlphaFold; in silico

(This special issue belongs to the Section Macromolecules)

Ion Channels in Physiology and Pathophysiology

edited by

Yonghui Zhao

and

Tarek Mohamed Abd El-Aziz

submission deadline 30 Sep 2026 | Viewed by 589 | Submission Open

Keywords: ion channels; physiology; pathophysiology; channelopathies; membrane proteins; cellular signaling; electrophysiology; structural biology; inflammation; therapeutic targets

(This special issue belongs to the Section Molecular Biology)

Nutritional Modulation of Lipid Metabolism and Gut–Tissue Axis: Mechanisms and Translational Insights

edited by

Piotr Dobrowolski

submission deadline 30 Sep 2026 | Viewed by 579 | Submission Open

Keywords: lipid metabolism; fatty acids; gut barrier; microbiota; metabolic programming; inflammation; FABP; nutrigenomics; obesity; zebrafish

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Research Progress in Food Packaging Materials

edited by

Anouar Mouhoub

submission deadline 30 Sep 2026 | 1 articles | Viewed by 579 | Submission Open

Keywords: molecular design; intermolecular interactions; structure–property relationships; bio-based polymers; controlled release systems; active packaging; sustainable materials

(This special issue belongs to the Section Materials Science)

CAR-T Cell Biology and Clinical Translation

edited by

Antonio Pérez Martínez

and

Daniel Ka Leung Cheuk

submission deadline 30 Sep 2026 | Viewed by 567 | Submission Open

Keywords: chimeric antigen receptor (CAR) T cells; gene engineering; genome editing; T‑cell exhaustion; tumor microenvironment; cytokine release syndrome (CRS); ICANS (immune effector cell–associated neurotoxicity syndrome); allogeneic CAR‑T cells; dual‑targeting CAR‑T cells; point‑of‑care manufacturing

(This special issue belongs to the Section Molecular Immunology)

Emerging Challenges for Renal Health-Biomarkers and Vulnerability to Xenobiotics

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 30 Sep 2026 | 1 articles | Viewed by 557 | Submission Open

Keywords: xenobiotics; nephrotoxicity; mechanisms of renal damage; molecular pathways; acute kidney injury; chronic kidney disease; novel renal biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Endocrine-Disrupting Chemicals in Reproductive Toxicity

edited by

Dragana Samardžija Nenadov

submission deadline 30 Sep 2026 | 1 articles | Viewed by 552 | Submission Open

Keywords: endocrine-disrupting chemicals (EDCs); reproductive toxicity; steroidogenesis; molecular mechanisms; intracellular signaling; hormone receptors; reproductive health

(This special issue belongs to the Section Molecular Toxicology)

Molecular Antimicrobial Resistance in Cancers

edited by Nicola Silvestris and Massimo Andreoni

submission deadline 30 Sep 2026 | Viewed by 548 | Submission Open

Keywords: antimicrobial resistance; host–pathogen interaction; immune dysfunction; immunosuppression; infection; biomarker; novel antimicrobials; cancer; frail patient

(This special issue belongs to the Section Molecular Oncology)

Next-Generation Sequencing in Cancer: Genomics, Diagnostics and Therapeutics

edited by Adam Szpechciński and Magdalena Pelc

submission deadline 30 Sep 2026 | 1 articles | Viewed by 547 | Submission Open

Keywords: next-generation sequencing (massively parallel sequencing); whole-genome sequencing (WGS); whole-exome sequencing (WES); RNA sequencing (RNA-seq); single-cell sequencing (SCS); germline and somatic mutations; gene rearrangements (fusions); epigenetics; molecular diagnostics; bioinformatics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Bioactive Lipids in Health and Disease: From Bench to Translational Insights

edited by

Claudio Bernal

submission deadline 30 Sep 2026 | 1 articles | Viewed by 530 | Submission Open

Keywords: functional lipids; lipids properties; fatty acids; lipid signaling; lipidomics; precision nutrition; cardiometabolic disease; inflammation; translational research

(This special issue belongs to the Section Bioactives and Nutraceuticals)

A Window to the Brain: From Retinal Cellular and Soluble Biomarkers Towards Neurodegeneration

edited by

Bijorn Omar Balzamino

,

Rosanna Squitti

and

Alessandra Micera

submission deadline 30 Sep 2026 | Viewed by 519 | Submission Open

Keywords: retinal signaling; oxidative stress; retinal neurodegeneration; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

T Cell Receptor (TCR) Signaling at the Crossroads of Immunity, Tolerance, and Disease

edited by Amar Singh

submission deadline 30 Sep 2026 | Viewed by 517 | Submission Open

Keywords: T cell receptor (TCR) signaling; immune tolerance; effector T cell differentiation; regulatory T cells (Tregs, Tr1); T cell heterogeneity; metabolic reprogramming; T cell memory and exhaustion; TCR repertoire analysis; autoimmunity and inflammation; TCR-based immunotherapy; CAR-T cells

(This special issue belongs to the Section Molecular Immunology)

Diverse Biomolecular Probes in the Development of Single-Molecule Biosensors

edited by

Kevin D. Belfield

and

Xiaohan Chen

submission deadline 30 Sep 2026 | Viewed by 517 | Submission Open

Keywords: biomolecular probes; single-molecule method; biosensors; diseases diagnosis; biomarkers; nanotechnology

(This special issue belongs to the Section Materials Science)

Cellular and Molecular Mechanisms of Biological Interactions with Carbon-Based Materials

edited by Ângela Almeida and

Francesca Coppola

submission deadline 30 Sep 2026 | 1 articles | Viewed by 513 | Submission Open

Keywords: carbon (nano)materials; (nano)toxicology; biomaterial interactions; biosensors; remediation; risk assessment

(This special issue belongs to the Section Molecular Nanoscience)

Transformation and Associated Isotope Kinetics of Halogenated Organic Pollutants in the Environment and Living Organisms

edited by Chenchen Huang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 510 | Submission Open

Keywords: halogenated organic pollutants; compound-specific isotope analysis; isotope fractionation; source apportionment; transformation discrimination; mechanism elucidation; biotic and abiotic transformation; transformation kinetics and pathways; environmental fate

(This special issue belongs to the Section Biochemistry)

Molecular Advances of Gut–Brain Communications

edited by

Walter Pirovano

submission deadline 30 Sep 2026 | Viewed by 508 | Submission Open

Keywords: gut-brain axis; microbiome; molecular profiling; omics/multi-omics data; functional measurements; analytical methods; computational methods; neurological disorders; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Biology)

Emerging Cardiovascular Drugs and Nutraceuticals: Mechanistic Insights, Translational Research and Clinical Impacts

edited by Pietro Mazzeo,

Vincenzo Vestuto

and Elena Mele

submission deadline 30 Sep 2026 | Viewed by 508 | Submission Open

Keywords: cardiovascular disease; drug mechanisms; nutraceuticals; precision medicine; multi-omics approaches

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in Electrochemical-Related Materials: 2nd Edition

edited by Celia García-Hernandez

submission deadline 30 Sep 2026 | 1 articles | Viewed by 503 | Submission Open

Keywords: novel electrochemical devices; advanced micro- and nanomaterials for electrochemical applications; batteries; fuel and photoelectrochemical cells; electrochemical sensors and biosensors; new advances in supercapacitors; electrochemical electrolyzers; advanced electrochemical materials for environmental applications

(This special issue belongs to the Section Materials Science)

Valorization of Agri-Food Wastes: Extraction, Characterization and Functional Applications of Bioactive Compounds

edited by Pittaya Chaikham

submission deadline 30 Sep 2026 | Viewed by 502 | Submission Open

Keywords: agri-food waste valorization; bioactive compounds; functional foods; green extraction; food sustainability; plant-based ingredients; antioxidants; circular economy; probiotics; food processing

(This special issue belongs to the Section Biochemistry)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 30 Sep 2026 | Viewed by 498 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Omega-6 and Omega-3 Fatty Acid Imbalance: Roles in Human Health and Pathogenesis of Diseases

edited by

Jing X. Kang

submission deadline 30 Sep 2026 | Viewed by 487 | Submission Open

Keywords: omega-6/omega-3 ratio; omega-6 fatty acids; omega-3 fatty acids; omega-6/omega-3 imbalance; lipid metabolism; inflammation; chronic diseases; cardiovascular disease; cancer; metabolic syndrome; neurodegenerative diseases; autoimmune diseases; nutritional interventions; polyunsaturated fatty acids (PUFAs); molecular mechanisms; disease pathogenesis; disease management; health promotion

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Computational Intelligence and Algorithmic Advances in Genome Editing

edited by

Anderson Rodrigues dos Santos

submission deadline 30 Sep 2026 | 1 articles | Viewed by 469 | Submission Open

Keywords: CRISPR/cas systems; genome engineering; bioinformatics; gRNA design; off-target prediction; machine learning; structural modeling; molecular informatics; DNA repair pathways

(This special issue belongs to the Section Molecular Informatics)

Pathogenic Escherichia coli: Cellular Biology, Mechanisms of Pathogenesis, Therapeutic Approaches and Strategies for Disease Intervention

edited by

Jorge Goldstein

submission deadline 30 Sep 2026 | Viewed by 461 | Submission Open

Keywords: enterohemorrhagic E. coli; EHEC; Shiga toxin-producing E. coli; STEC; HUS; inflammation; kidney; blood; brain; pathogenesis; antibodies; extraintestinal pathogenic E. coli; E. coli pathotypes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Immune Mechanisms in Kidney Disease

edited by Niels Olsen Saraiva Câmara

submission deadline 30 Sep 2026 | Viewed by 454 | Submission Open

Keywords: kidney disease; molecular sensors; kidney metabolism; immunity; AKI to CKD transition

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Patient-Derived iPSC Models in Chronic Disease Research

edited by

Valentina Parra

submission deadline 30 Sep 2026 | Viewed by 453 | Submission Open

Keywords: induced pluripotent stem cells; patient-derived iPSCs; chronic diseases; disease modeling; molecular mechanisms; stem cell differentiation; gene editing; organoids; personalized medicine; multi-omics

(This special issue belongs to the Section Molecular Biology)

Novel Molecular Pathways and Therapeutic Strategies in Atherosclerotic Cardiovascular Disease

edited by

Elisabeta Badila

and Catalin Adrian Buzea

submission deadline 30 Sep 2026 | Viewed by 437 | Submission Open

Keywords: atherogenesis; vascular inflammation; immune modulation; lipid metabolism; clonal hematopoiesis (CHIP); endothelial dysfunction; plaque instability; epigenetic regulation; molecular signaling pathways; precision cardiovascular medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Molecular Plant Physiology and Genomic Breeding of Cereals

edited by

Abdullah Shalmani

submission deadline 30 Sep 2026 | Viewed by 434 | Submission Open

Keywords: cereals; molecular physiology; genomic breeding; stress tolerance; functional genomics; genome editing; QTL mapping; multiomics; genotype–environment interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Gut Microbiota-Mediated Drug Efficacy and Toxicity

edited by

Jin-Yi Wan

submission deadline 30 Sep 2026 | Viewed by 422 | Submission Open

Keywords: gut microbiota; pharmacomicrobiomics; drug metabolism; drug toxicity; drug efficacy; xenobiotic biotransformation; precision medicine; cancer immunotherapy; fecal microbiota transplantation; host–microbiome interactions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

DNA Damage, DNA Repair, and Cancer, 3rd Edition

edited by

Kazuhiko Kuwahara

submission deadline 30 Sep 2026 | 1 articles | Viewed by 418 | Submission Open

Keywords: DNA-damage response; DNA repair molecules; genome instability; cellular senescence; animal models; DNA damage; DNA repair and cancer

(This special issue belongs to the Section Molecular Oncology)

Metabolomics in Cancer: From Biomarkers to Therapeutic Insights

edited by Filipa Amaro,

Paula Guedes de Pinho

and

Joana Pinto

submission deadline 30 Sep 2026 | Viewed by 413 | Submission Open

Keywords: cancer metabolomics; metabolic reprogramming; biomarker discovery; precision oncology; machine learning; clinical data integration; translational cancer research

(This special issue belongs to the Section Molecular Oncology)

Genome-Wide Association Studies of Complex Diseases and Related Endophenotypes and Biomarkers

edited by M. Ilyas Kamboh

submission deadline 30 Sep 2026 | Viewed by 410 | Submission Open

Keywords: genome-wide association studies; complex diseases; endophenotypes; biomarkers; rare variants; copy number variants; diverse populations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Inflammatory Bowel Disease and Cardiometabolic Comorbidities: Molecular Mechanisms and Therapeutic Perspectives

edited by

Dimitrios Patoulias

and

Christos Mademlis

submission deadline 30 Sep 2026 | Viewed by 403 | Submission Open

Keywords: cardiovascular–kidney–metabolic syndrome; diabetes; obesity; cardiovascular disease; inflammatory bowel disease; Crohn’s disease; ulcerative colitis; inflammation; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Integrating Multi-Omics Approaches in Fish Immunology to Improve Aquaculture Sustainability

edited by

Parasuraman Aiya Subramani

submission deadline 30 Sep 2026 | Viewed by 402 | Submission Open

Keywords: machine learning; network analysis; vaccine development; genomic selection; single-cell RNA-seq; meta-analysis; innate immunity; biomarker discovery

(This special issue belongs to the Section Molecular Immunology)

Novel Insights into Endothelial Cell Biology

edited by

Takato Hara

and

Toshiyuki Kaji

submission deadline 30 Sep 2026 | Viewed by 392 | Submission Open

Keywords: endothelial cell heterogeneity; mechanotransduction; endothelial–immune interactions; endothelial senescence; vascular barrier regulation; extracellular vesicles; angiogenesis and vascular remodeling; endothelial metabolism; endothelial regulation of the fibrinolytic system

(This special issue belongs to the Section Molecular Biology)

Fungi: From Molecular Biology to Biotechnology Applications

edited by

Ljiljana Janjušević

and

Ljiljana Šašić Zorić

submission deadline 30 Sep 2026 | 1 articles | Viewed by 384 | Submission Open

Keywords: fungi; fungal secondary metabolome; fungal bioactive compounds; edible and medicinal fungi; nutraceuticals; functional foods; fungal biotechnology; metabolomics; fungal natural products; fungal metabolism

(This special issue belongs to the Section Molecular Microbiology)

Genetic Diversity, Founder Effects, and Migration in Neurodegeneration: Molecular and Population Perspectives

edited by

Dasiel Oscar Borroto-Escuela

submission deadline 30 Sep 2026 | Viewed by 382 | Submission Open

Keywords: neurodegeneration; population genetics; founder effects; genetic diversity; migration and disease risk; spinocerebellar ataxia; Alzheimer’s disease; Parkinson’s disease; genetic epidemiology; underrepresented populations

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Interplay: Natural Antioxidants as Modulators of Redox Homeostasis

edited by

Giovanni Pratelli

and

Daniela Carlisi

submission deadline 30 Sep 2026 | Viewed by 382 | Submission Open

Keywords: natural antioxidants; oxidative stress; chronic diseases; molecular mechanisms; cancer; neurodegenerative diseases; metabolic disorders; redox biology; omics; precision medicine

(This special issue belongs to the Section Molecular Biology)

Advances in Therapeutic Antibody Engineering

edited by

Chatchai Tayapiwatana

submission deadline 30 Sep 2026 | Viewed by 382 | Submission Open

Keywords: therapeutic antibodies; bispecific antibodies; antibody-drug conjugates (ADCs); nanobodies; AI-driven drug design; Fc engineering; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Molecular Determinants of Cardiovascular Diseases

edited by

Susan Darroudi

submission deadline 30 Sep 2026 | Viewed by 376 | Submission Open

Keywords: atherosclerosis; hypertension; diabetes; dyslipidemia; endothelial dysfunction; vascular remodeling; inflammation and oxidative stress; mitochondrial dysfunction; molecular diagnostics; heart function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Pituitary Neuroendocrine Tumors: From Growth Control to Plasticity and Evolutionary Pathogenesis

edited by Ana Lucía De Paul and Liliana del Valle Sosa

submission deadline 30 Sep 2026 | Viewed by 363 | Submission Open

Keywords: tumor heterogeneity; tumor biomarkers; transcriptomics; molecular neuroscience; clinical treatment; pathogenesis; pituitary neuroendocrine tumors; neuroendocrine tumors; nonfunctional; PIT1; pituitary adenoma

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Role of Bifunctional Antibodies in Human Cancer

edited by

Alessandro Canella

submission deadline 30 Sep 2026 | Viewed by 362 | Submission Open

Keywords: bispecific antibodies; tumor immune microenvironment (TIME); cancer immunotherapy; tumor associated antigens; biomarker discovery; T cell engagers (BiTEs, TriTEs, TriKEs); dual affinity retargeting antibodies (DARTs); Fc engineering and FcγR modulation; tumor associated antigen (TAA) avidity optimization; immune reprogramming; bispecific antibody pharmacokinetics and biodistribution; antibody–drug conjugate (ADC) hybrid formats; bifunctional antibodies

(This special issue belongs to the Section Molecular Oncology)

Molecular Studies of Cartilage Deformation

edited by

Kazuo Yudoh

submission deadline 30 Sep 2026 | Viewed by 361 | Submission Open

Keywords: osteoarthritis; chondrocyte; mitochondria function; mechanical stress; oxidative stress; cartilage metabolism

(This special issue belongs to the Section Molecular Biology)

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