Special Issue "Translocator Protein (TSPO) in Drug Delivery and Imaging of Pathological Disorders"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 March 2019).
Prof. Dr. Giovanni Natile
Department of Chemistry, University of Bari "Aldo Moro", via E. Orabona 4, 70125 Bari, Italy
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Interests: transport of anti-tumoral platinum-based drugs and their interaction with proteins and DNA; non-classic platinum anticancer drugs; active trans-platinum compounds; platinum compounds with uncommon coordination numbers and oxidation states and activation of unsaturated ligands
The increasing interest in the 18-kDa mitochondrial translocator protein (TSPO), as evidenced by the success of the previous Special Issue on the latest findings on the role of TSPO in eukaryotic cells, led us to propose a second Special Issue of the International Journal of Molecular Sciences on the role of the Translocator Protein in the drug delivery and imaging of pathological disorders.
TSPO is emerging as an extremely attractive subcellular biomarker for the early detection of disease states overexpressing this protein, and for the selective delivery of drugs to mitochondria. Moreover, the design and synthesis of new, more specific and effective TSPO ligands remains a very valuable task that cannot be neglected. Submissions dealing with all of these topics are welcome.
Prof. Dr. Nunzio Denora
Prof. Dr. Giovanni Natile
Manuscript Submission Information
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- Translocator Protein 18-kDa
- TSPO ligand
- drug delivery
- drug targeting