Molecular Research in Primary Osteoporosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 January 2024) | Viewed by 2697
Special Issue Editors
Interests: neurodegenerative diseases; Alzheimer’s disease; depression; anxiety; memory; learning; ageing; neuroinflammation; neurotrophic factors; sinaptic plasticity; cell biology; irisin; prefrontal cortex; hippocampus; histology; electron microscopy
Special Issues, Collections and Topics in MDPI journals
Interests: multiple myeloma bone disease; bone remodeling; citokynes and bone mass modulation; angiogenesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Primary osteoporosis, a frequent disorder of bone remodeling process, is characterized by the decrease in bone mass and mineral density (BMD). Because of the impairment in bone quality and microarchitecture, osteoporotic patients are more exposed to low-energy fractures in long bones and vertebrae than normal population. Primary osteoporosis predominantly affects postmenopausal women (type I osteoporosis) and the elderly population (type II osteoporosis); therefore, this skeletal disorder is often considered as an aging-associated disease. However, an idiopathic juvenile osteoporosis that may occur in children and young adults has also been described.
The high prevalence of primary osteoporosis increased the interest of the research to shed light on its pathogenesis trying to improve its current prevention and treatment methods.
In line with this aim, in this Special Issue, we welcome molecular- or cellular-level original research articles and comprehensive reviews relating to molecular pathophysiology and targeted therapies of this topic. Submissions of clinical studies with biomolecular experiments or pathological research with case sample data are also welcomed.
Dr. Manuela Dicarlo
Dr. Angela Oranger
Guest Editors
Manuscript Submission Information
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Keywords
- idiopathic juvenile osteoporosis
- postmenopausal osteoporosis
- senile osteoporosis
- bone loss
- bone fragility
- ageing
