Bioinformatics Study in Human Diseases: Integration of Omics Data for Personalized Medicine (Third Edition)

Dear Colleagues,

In the past decade, unprecedented breakthroughs have emerged from the application of next-generation sequencing technologies and advanced artificial intelligence methods. These advances have created remarkable opportunities for identifying key companion biomarkers and biosignatures, improving diagnosic efficiency, enhancing prognostic prediction, accelerating drug discovery, and uncovering potential mechanisms in a comprehensive, multi-omics-driven manner.

Bioinformatics is widely employed to address these challenges. A variety of bioinformatics tools and open access datasets have been developed to integrate omics data—including epigenomics, metabolomics, transcriptomics, and genomics—comprehensively. Compared withe traditional approaches, bioinformatics has considerably improved diagnostic and prognostic accuracy, expedited the discovery of novel drug targets, and deepened the functional understanding of disease mechanisms, paving the way toward advances in precision medicine.

We are pleased to invite you to contribute original research articles related to (but not limited to) bioinformatics-centric identification of biomarkers, biosignatures, drug candidates, mechanisms, or predictive algorithms for diagnosis, prognosis, and potential therapeutics in human diseases. Critical review manuscripts offering forward-looking perspectives and outlining future research directions are also especially welcome.

Please kindly note that new methods must be compared with existing state-of-the-art approaches using real biological datasets. The inclusion of experimental validation is highly encouraged.

We look forward to receiving your contributions.

Dr. Hung-Yu Lin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.