Special Issue "Molecular Genetics of Prion Diseases"
Deadline for manuscript submissions: closed (31 December 2020).
Interests: prion diseases; neurodegenerative disorders; prion protein gene (PRNP); prion-like protein gene (PRND); shadow of prion protein gene (SPRN); prion-related protein gene (PRNT); population genetics; genomics; bioinformatics
Prion disease is fatal, acute and irreversible neurodegenerative diseases with wide host ranges, including scrapie in sheep and goats, bovine spongiform encephalopathy (BSE) in cattle, chronic wasting disease (CWD) in elk and deer, and Creutzfeldt–Jakob disease (CJD) in humans. It has been approximately three centuries since prion disease in sheep was first discovered in 1732. However, the exact mechanism on the progression and the causative agent of prion diseases have not been revealed thus far. To date, genetic variations including genetic polymorphisms, germline mutations and somatic mutations of the prion disease-related genes play pivotal role in prion diseases.
In this Special Issue of the International Journal of Molecular Sciences, the main topic will be “Molecular genetics of prion diseases”, which is dedicated to research articles and reviews of prion disease-related genetic studies, including human and non-human studies. The emphasis will be on novel prion disease-related genetic variabilities and prion disease susceptibilities and the functional role of prion disease-related genes to understand the pathogenesis of prion diseases.
Dr. Byung-Hoon Jeong
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Prion diseases
- Prion protein gene (PRNP)
- Prion-like protein gene (PRND)
- Shadow of prion protein gene (SPRN)
- Prion-related protein gene (PRNT)
- Prion disease-candidate genes