Special Issue "Bioactive Phytochemicals in Functional Foods for Cancer Prevention"
Deadline for manuscript submissions: closed (20 February 2015)
Prof. Dr. Sanjay K. K. Srivastava
1. Distinguished Professor and Chairman, Department of Immunotherapeutics and Biotechnology, Suite 1305, 1718 Pine Street, Abilene, TX 79601, USA
2. Associate Dean for Sciences, Suite 2101 ARB, Texas Tech University Health Sciences Center, 1406 Coulter Drive, Amarillo, TX 79106, USA
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Interests: development of phytochemicals for cancer prevention and therapeutics; targeting STAT-3, NF-kB, HER2, MCL-1, AKT/FOXO, GLI1/2, and related signaling pathways with agents such as capsaicin, piperlongumine, penfluridol, isothiocyanates, diindolylmethane, panabinostat, cucurbitacin B, and deguelin in pancreatic, ovarian, breast, melanoma, and brain cancer; drug repurposing
Prof. Dr. Sung-Hoon Kim
Department of Oriental Pathology, College of Oriental Medicine, Kyunghee University, Seoul, South Korea
Interests: development of chemopreventive cancer agents (metastasis and angiogenesis inhibitors) and functional food (pharmaceuticals); isolation of effective compounds for the prevention or treatment of kidney stones from medicinal herbs
Plants have been an important source of bioactive phytochemicals since historic times. Phytochemicals are synthesized by plants as their defensive mechanisms. Several epidemiological studies indicate inverse correlation between intake of specific plant foods and cancer incidence. Thousands of phytochemicals have been identified to date, but only a few have been explored in depth for their beneficial roles. Phytochemicals available from dietary plant sources can be classified based on their chemical structures. For example, isothiocyanates, indoles, carotenoids, flavonoids, isoflavones, terpenoids are some of the major classes studied for their anti-cancer effects. Phytochemicals are considered to be advantageous over current chemotherapeutic options available. This is because cancer etiology involves multiple mechanisms, and phytochemicals, being pleiotropic, can counter more pro-carcinogenic mechanisms. Moreover, being a component of dietary plants, phytochemicals are also relatively non-toxic and generally have broader safety windows. This special issue has been envisaged to document studies on well-known phytochemicals and their role in cancer prevention. The articles in this issue are contributed by eminent researchers in the field of cancer chemoprevention, all around the world. This issue will be beneficial to all the basic, clinical and applied researchers and physicians interested in cancer chemoprevention.
Prof. Dr. Sanjay K. Srivastava
Prof. Dr. Sung-Hoon Kim
Manuscript Submission Information
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- dietary agents
- functional foods
- bioactive agents
- molecular mechanism
- signaling mechanism
- cell cycle