Molecular Mechanisms of Cancer Invasion and Metastasis

Dear Colleagues,

Cancer invasion and metastasis pose significant challenges in the field of oncology, being a leading cause of cancer-related deaths. Understanding the molecular basis of these processes is vital for developing effective treatments and holds the potential to significantly improve patient outcomes and mitigate the global impact of cancer.

This Special Issue aims to explore the molecular mechanisms that underlie cancer invasion and metastasis. Our objective is to cover a wide array of research that investigates the mechanisms underlying processes involved in the following:

• Cancer cell interactions with the tumor microenvironment;
• Cancer cell motility;
• Invasion into surrounding tissues;
• Vascular and lymphatic intra- and extravasation;
• Survival in the bloodstream;
• Dissemination at distant sites;
• Establishment of secondary tumor growth.

We seek to feature original research papers and reviews that provide insight into the molecular mechanisms behind signaling pathways, genetic and epigenetic changes, biochemical and mechanical environmental cues, immune interactions, and susceptibility to treatment implicated in cancer invasion and metastasis. Furthermore, we aim to highlight emerging technologies and experimental models that help us improve our understanding of these crucial aspects of cancer development.

Ultimately, this Special Issue seeks to serve as a knowledge-sharing platform for interdisciplinary discussions among researchers and clinicians who uncover the molecular bases of cancer invasion and metastasis. By bringing together diverse insights and discoveries, we aim to improve efforts in developing effective strategies for dealing with metastatic disease and improving patient outcomes.

Dr. Zbigniew Baster
Guest Editor

Manuscript Submission Information

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