Redox Enzymes: Molecular Mechanisms, Structural Features, Physiological Roles
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1359
Special Issue Editor
Interests: biochemistry; molecular mechanisms of enzyme action; molecular bioenergetics; membrane proteins; respiratory chains; terminal oxidases; cytochromes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Redox enzymes are enzymes that catalyze biological electron transfer reactions and carry redox-active cofactors for this purpose. Among the redox enzymes are protein complexes of the respiratory chains of mitochondria and bacteria, enzymes involved in photosynthetic metabolism, ROS scavenging enzymes including superoxide dismutases, peroxidases, and catalases, and many others. Redox proteins are the core of the enzymatic antioxidant machinery which helps organisms to prevent or reduce ROS-induced oxidative stress. The investigation of the molecular mechanisms of the energy-transducing redox enzymes allows us to clarify the features of the device and the design of artificial membranes and nanosystems that are able to efficiently convert different forms of energy. The study of respiratory chain enzymes is extremely important and promising from a biomedical point of view. In particular, a comparative study of the heme-copper oxidases and the cytochrome bd oxidases may contribute to the development of new-generation antibiotics.
This Special Issue aims to collect the results of new insights into the molecular mechanisms and structure of the respiratory chain, light-transducing and ROS scavenging enzymes, their physiological roles, assembly pathways, biotechnological applications, and utility as drug targets. Original research articles and up-to-date reviews on these and related topics are welcome in this Special Issue.
Prof. Dr. Vitaliy Borisov
Guest Editor
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Keywords
- metalloenzyme
- terminal oxidase
- cytochrome
- heme
- respiratory chain
- photosynthesis
- enzyme activation and inhibition
- ROS scavenging enzyme
- reactive oxygen species
- ROS defense mechanism
- molecular bioenergetics
- drug target
