Liver Pathophysiology and Its Role in Systemic Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 78
Special Issue Editor
Interests: viral hepatitis; steatotic liver disease; liver cirrhosis; hepatocellular carcinoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The project is conducted in collaboration with Topical Advisory Panel Member, Dr. Eleni Geladari.
The liver is the hub of multiple biochemical processes. This highly regenerative organ guards immunity by synthesizing immune factors and vitamins and balances the coagulation system by producing pro- and anticoagulant molecules. Since the liver regulates metabolism through hormones with auto-, para-, and endocrine functions, it is considered the largest endocrine gland. Its ability to detoxify toxic agents protects other tissues. In addition, the liver has a tremendous storage capacity of vitamins, minerals, and numerous other essential substances. The liver supplies the biliary system and regulates lipid metabolism and energy homeostasis. Because of that, the liver contributes to numerous systemic diseases, and accordingly, liver-targeted drugs can be used for their treatments. The goal of this Special Issue is to acknowledge the biological linkage between the liver and other tissues and highlight the importance of this cross-talk for disease development.
Dr. Vassilios Sevastianos
Guest Editor
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Keywords
- liver disease
- endocrine functions
- liver-targeted drugs
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