Pain in Human Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 25 November 2025 | Viewed by 253
Special Issue Editor
2. Institute for Research and Innovation in Health and IBMC (i3S), University of Porto, 4200-135 Porto, Portugal
Interests: pain; temporomandibular disorders; sleep disorders; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pain is a complex and fascinating physiological and pathological phenomenon that plays a critical role in human health and disease. Understanding the molecular mechanisms underlying pain is essential for developing effective therapeutic strategies. This Special Issue of the IJMS aims to explore the intricate molecular and cellular pathways involved in pain signaling, modulation, chronic pain development, and its relationship with other physiological aspects of health, including cognitive and emotional disturbances.
We invite submissions investigating the molecular basis of pain in various contexts, including acute and chronic pain conditions, neuropathic pain, orofacial pain, and pain associated with inflammatory and degenerative diseases. Manuscripts focusing on novel molecular targets, signaling pathways, epigenetic regulation, and interactions between the nervous and immune systems are particularly encouraged. Research and up-to-date reviews exploring cutting-edge therapeutic approaches, such as pharmacogenomics, gene editing, molecular inhibitors, and nanotechnology-based drug delivery systems, are also of significant interest.
Dr. Daniel Pozza
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pain signaling
- molecular pathways
- chronic pain
- neuropathic pain
- inflammation neuro–immune interactions
- epigenetics pharmacogenetics
- precion medicine
- sleep disorders
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